Tyr349

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Phosphorylation Site Page:

Site Information

IQAAWRYyATNPNRL SwissProt Entrez-Gene

Predicted information: Scansite

Orthologous residues: Kv7.3 (rat): Y387, Kv7.3 iso3 (mouse): Y384, Kv7.3 (mouse): Y387, Kv7.3 (human): Y386

Blast this site against: NCBI SwissProt PDB

In vivo Characterization

Methods used to characterize site in vivo:	mutation of modification site (1), phospho-antibody (1), western blotting (1)
Relevant cell line - cell type - tissue:	CHO (fibroblast) [EphB1 (human), transfection] (1)

Controlled by

Putative upstream kinases:

Src (rat) (1)

Downstream Regulation

Effects of modification on Kv7.3 iso2:

inhibition (1)

	References

1	Li Y, et al. (2004) Dual phosphorylations underlie modulation of unitary KCNQ K(+) channels by Src tyrosine kinase. J Biol Chem 279, 45399-407 15304482 Curated Info

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