Ser57
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Phosphorylation Site Page:
Ser57 - PWP1 (human)

Site Information
SDEEETGsPSEDGMQ    SwissProt Entrez-Gene
Predicted information: Scansite
Orthologous residues: PWP1 (mouse): N56
Blast this site against: NCBI  SwissProt  PDB 

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (2, 3, 4, 5, 6, 7, 8, 9)
Disease tissue studied: cervical cancer (3, 4), cervical adenocarcinoma (3, 4), leukemia (8), chronic myelogenous leukemia (8)
Relevant cell line - cell type - tissue: 293 (epithelial) [AT1 (human), transfection, AT1R stable transfected HEK293] (2), HeLa (cervical) (6, 9), HeLa S3 (cervical) (3, 4), Jurkat (T lymphocyte) (5), K562 (erythroid) (7, 8)

Controlled by
Treatments: nocodazole (3)



References

1

Shiromizu T, et al. (2013) Identification of Missing Proteins in the neXtProt Database and Unregistered Phosphopeptides in the PhosphoSitePlus Database As Part of the Chromosome-Centric Human Proteome Project. J Proteome Res
23312004   Curated Info

2

Christensen GL, et al. (2010) Quantitative phosphoproteomics dissection of seven-transmembrane receptor signaling using full and biased agonists. Mol Cell Proteomics 9, 1540-53
20363803   Curated Info

3

Olsen JV, et al. (2010) Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. Sci Signal 3, ra3
20068231   Curated Info

4

Malik R, et al. (2009) Quantitative analysis of the human spindle phosphoproteome at distinct mitotic stages. J Proteome Res 8, 4553-63
19691289   Curated Info

5

Mayya V, et al. (2009) Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. Sci Signal 2, ra46
19690332   Curated Info

6

Dephoure N, et al. (2008) A quantitative atlas of mitotic phosphorylation. Proc Natl Acad Sci U S A 105, 10762-7
18669648   Curated Info

7

(2008) CST Curation Set: 4609; Year: 2008; Biosample: K562; Disease: chronic myelogenous leukemia; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-[sty](phosphorylation)
Curated Info

8

(2008) CST Curation Set: 4393; Year: 2008; Biosample: K562; Disease: chronic myelogenous leukemia; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-[sty](phosphorylation)
Curated Info

9

Beausoleil SA, et al. (2004) Large-scale characterization of HeLa cell nuclear phosphoproteins. Proc Natl Acad Sci U S A 101, 12130-5
15302935   Curated Info

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