Ser754
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Phosphorylation Site Page:
Ser754 - GTF3C1 (human)

Site Information
GSGDSQLsASSRSES    SwissProt Entrez-Gene
Predicted information: Scansite
Orthologous residues: GTF3C1 (rat): N753, GTF3C1 (mouse): N754
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 14736386

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (1, 2, 4)
Relevant cell line - cell type - tissue: GM00130 (B lymphocyte) (4), HeLa (cervical) (1, 2)

Controlled by
Treatments: ionizing radiation (4)



References

1

Sharma K, et al. (2014) Ultradeep human phosphoproteome reveals a distinct regulatory nature of Tyr and Ser/Thr-based signaling. Cell Rep 8, 1583-94
25159151   Curated Info

2

(2011) CST Curation Set: 11708; Year: 2011; Biosample/Treatment: cell line, HeLa/UV; Disease: cervical adenocarcinoma; SILAC: -; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-(s/t)Q(phosphorylation) Antibody Used to Purify Peptides prior to MS2: Phospho-(Ser/Thr) ATM/ATR Substrate (S*/T*QG) (P-S/T2-100) Rabbit mAb Cat#: 6966, PTMScan(R) Phospho-ATM/ATR Substrate Motif (S*/T*QG) Immunoaffinity Beads Cat#: 6969
Curated Info

3

Phanstiel DH, et al. (2011) Proteomic and phosphoproteomic comparison of human ES and iPS cells. Nat Methods 8, 821-7
21983960   Curated Info

4

Bennetzen MV, et al. (2010) Site-specific phosphorylation dynamics of the nuclear proteome during the DNA damage response. Mol Cell Proteomics 9, 1314-23
20164059   Curated Info

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