Tyr553
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Phosphorylation Site Page:
Tyr553 - Kit (human)

Site Information
KYLQKPMyEVQWKVV    SwissProt Entrez-Gene
Predicted information: Scansite
Orthologous residues: Kit (mouse): Y556
Blast this site against: NCBI  SwissProt  PDB 

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (in vitro) (1)

Controlled by
Kinases, in vitro: Kit (human) (1)

Downstream Regulation
Effects of modification on Kit: enzymatic activity, induced (1)


References

1

DiNitto JP, et al. (2010) Function of activation loop tyrosine phosphorylation in the mechanism of c-Kit auto-activation and its implication in sunitinib resistance. J Biochem 147, 601-9
20147452   Curated Info

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