Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
HomeAbout PhosphoSiteUsing PhosphoSiteCuration ProcessContact
logos LINCs Logo Mt Sinai Logo NIH Logo NCI Logo
Phosphorylation Site Page:
Ser105 - Tau iso3 (human)

Site Information
GDRSGYSsPGSPGTP   SwissProt Entrez-Gene
Predicted information:  Scansite
Orthologous residues: Tau (rat): S510, Tau (human): S516, Tau iso8 (human): S199, Tau (mouse): S491, Tau iso5 (human): S199, Tau iso7 (human): (S170), Tau iso7 (mouse): (S148), Tau iso3 (mouse): (S188), Tau (cow): (S206), Tau iso6 (human): (S141), Tau iso2 (human): (S141)
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 447927

In vivo Characterization
Methods used to characterize site in vivo: mutation of modification site (1)
Disease tissue studied: adrenal cancer (1), pheochromocytoma (1)
Relevant cell line - cell type - tissue: PC-12 (chromaffin) (1)

Controlled by
Treatments: okadaic_acid (1)

Downstream Regulation
Effects of modification on Tau iso3: molecular association, regulation (1)
Effects of modification on biological processes: cytoskeletal reorganization (1)



Maas T, Eidenm├╝ller J, Brandt R (2000) Interaction of tau with the neural membrane cortex is regulated by phosphorylation at sites that are modified in paired helical filaments. J Biol Chem 275, 15733-40
10747907   Curated Info

Home  |  Curator Login With enhanced literature mining using Linguamatics I2E I2E Logo Produced by 3rd Millennium  |  Design by Digizyme
©2003-2013 Cell Signaling Technology, Inc.