Ser959
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Phosphorylation Site Page:
Ser959 - Kit (human)

Site Information
DHSVRINsVGSTASS   SwissProt Entrez-Gene
Predicted information:  Scansite
Orthologous residues: Kit (rat): S961, Kit (mouse): (S962)
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450038

In vivo Characterization
Methods used to characterize site in vivo: [32P] bio-synthetic labeling (3), mass spectrometry (1, 2), mutation of modification site (3), phosphoamino acid analysis (3)
Disease tissue studied: breast cancer (1), breast cancer, triple negative (1)
Relevant cell line - cell type - tissue: breast (1), HCT116 (intestinal) (2), MDA-MB-435S (breast cell) (2), PAE (endothelial) (3)

Controlled by
Treatments: SCF (3)



References

1

Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 13, 1690-704
24719451   Curated Info

2

Oppermann FS, et al. (2009) Large-scale proteomics analysis of the human kinome. Mol Cell Proteomics 8, 1751-64
19369195   Curated Info

3

Blume-Jensen P, Wernstedt C, Heldin CH, Rönnstrand L (1995) Identification of the major phosphorylation sites for protein kinase C in kit/stem cell factor receptor in vitro and in intact cells. J Biol Chem 270, 14192-200
7539802   Curated Info

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