Ser492
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Phosphorylation Site Page:
Ser492 - MCT1 (rat)

Site Information
GDPAEEEsPV_____   SwissProt Entrez-Gene
Orthologous residues: MCT1 iso4 (human): S478, MCT1 (human): S498, MCT1 (mouse): S491
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 468178

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (1, 2, 3, 4, 5)
Disease tissue studied: type 2 diabetes (5)
Relevant cell line - cell type - tissue: 'brain, brainstem' (3), 'brain, cerebellum' (3), 'brain, cerebral cortex' (3), 'kidney, cortex' (4), adipose tissue (3), blood (3), heart (3), IEC-6 (epithelial) (1), intestine (3), kidney (3), liver (3, 5), lung (3), muscle (3), PC-12 (chromaffin) (2), PC-12 (chromaffin) [TrkA (rat), transfection] (2), spleen (3), testis (3), thymus (3)




References

1

Courcelles M, et al. (2013) Phosphoproteome dynamics reveal novel ERK1/2 MAP kinase substrates with broad spectrum of functions. Mol Syst Biol 9, 669
23712012   Curated Info

2

Biarc J, Chalkley RJ, Burlingame AL, Bradshaw RA (2012) The induction of serine/threonine protein phosphorylations by a PDGFR/TrkA chimera in stably transfected PC12 cells. Mol Cell Proteomics 11, 15-30
22027198   Curated Info

3

Lundby A, et al. (2012) Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. Nat Commun 3, 876
22673903   Curated Info

4

Feric M, et al. (2011) Large-scale phosphoproteomic analysis of membrane proteins in renal proximal and distal tubule. Am J Physiol Cell Physiol 300, C755-70
21209370   Curated Info

5

Deng WJ, et al. (2010) Proteome, phosphoproteome, and hydroxyproteome of liver mitochondria in diabetic rats at early pathogenic stages. Mol Cell Proteomics 9, 100-16
19700791   Curated Info

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