Tyr757
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Phosphorylation Site Page:
Tyr757 - APP (rat)

Site Information
SKMQQNGyENPTYKF   SwissProt Entrez-Gene
Predicted information:  Scansite
Orthologous residues: APP iso4 (human): Y682, APP (human): Y757, APP iso2 (mouse): Y682, APP iso8 (human): Y738, APP (mouse): Y757, APP iso10 (human): (Y626), APP iso2 (rat): (Y682)
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448202

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (1, 2)
Disease tissue studied: adrenal cancer (2), pheochromocytoma (2)
Relevant cell line - cell type - tissue: brain (1), PC-12 (chromaffin) (2)




References

1

Tucker M (2009) CST Curation Set: 6767; Year: 2009; Biosample/Treatment: tissue, brain/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

2

Stokes M (2008) CST Curation Set: 4009; Year: 2008; Biosample/Treatment: cell line, PC-12/EGF; Disease: pheochromocytoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

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