Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
HomeAbout PhosphoSiteUsing PhosphoSiteCuration ProcessContact
logos LINCs Logo Mt Sinai Logo NIH Logo NCI Logo
Phosphorylation Site Page:
Thr156 - AP2M1 (rat)

Site Information
SQITSQVtGQIGWRR   SwissProt Entrez-Gene
Predicted information:  Scansite
Orthologous residues: AP2M1 (human): T156, AP2M1 (mouse): T156, AP2M1 iso2 (human): T154, AP2M1 iso3 (mouse): T154
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448782

In vivo Characterization
Methods used to characterize site in vivo: mutation of modification site (2)
Relevant cell line - cell type - tissue: HeLa (cervical) [AP2M1 (rat)] (2)

Downstream Regulation
Effects of modification on AP2M1: intracellular localization (2), molecular association, regulation (1), protein conformation (1)
Induce interaction with: TGOLN2 (human) (1)



Höning S, et al. (2005) Phosphatidylinositol-(4,5)-bisphosphate regulates sorting signal recognition by the clathrin-associated adaptor complex AP2. Mol Cell 18, 519-31
15916959   Curated Info


Olusanya O, Andrews PD, Swedlow JR, Smythe E (2001) Phosphorylation of threonine 156 of the mu2 subunit of the AP2 complex is essential for endocytosis in vitro and in vivo. Curr Biol 11, 896-900
11516654   Curated Info

Home  |  Curator Login With enhanced literature mining using Linguamatics I2E I2E Logo Produced by 3rd Millennium  |  Design by Digizyme
©2003-2013 Cell Signaling Technology, Inc.