Thr156
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Phosphorylation Site Page:
Thr156 - AP2M1 (rat)

Site Information
SQITSQVtGQIGWRR   SwissProt Entrez-Gene
Predicted information:  Scansite
Orthologous residues: AP2M1 (human): T156, AP2M1 (mouse): T156, AP2M1 iso2 (human): T154, AP2M1 iso3 (mouse): T154
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448782

In vivo Characterization
Methods used to characterize site in vivo: mutation of modification site (2)
Relevant cell line - cell type - tissue: HeLa (cervical) [AP2M1 (rat)] (2)


Downstream Regulation
Effects of modification on AP2M1: intracellular localization (2), molecular association, regulation (1), protein conformation (1)
Induce interaction with: TGOLN2 (human) (1)


References

1

Höning S, et al. (2005) Phosphatidylinositol-(4,5)-bisphosphate regulates sorting signal recognition by the clathrin-associated adaptor complex AP2. Mol Cell 18, 519-31
15916959   Curated Info

2

Olusanya O, Andrews PD, Swedlow JR, Smythe E (2001) Phosphorylation of threonine 156 of the mu2 subunit of the AP2 complex is essential for endocytosis in vitro and in vivo. Curr Biol 11, 896-900
11516654   Curated Info

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