Ser260
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Phosphorylation Site Page:
Ser260 - CDP138 (mouse)

Site Information
AFLPACSsPSRELKE   SwissProt Entrez-Gene
Predicted information:  Scansite
Orthologous residues: CDP138 (human): S260, CDP138 iso2 (mouse): (S260), CDP138 iso2 (human): (S260), CDP138 (rat): (S260)
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 453599

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (1, 2, 3, 4, 5, 6, 7, 8, 9)
Disease tissue studied: anthrax infection (5)
Relevant cell line - cell type - tissue: '3T3-L1, differentiated' (adipocyte) (1), 'brain, cerebral cortex' (8, 9), brain (6, 7), kidney (6), liver (3), liver [leptin (mouse), homozygous knockout] (3), lung (6), macrophage-peritoneum [RIP3 (mouse), homozygous knockout] (2), MEF (fibroblast) (2), MEF (fibroblast) [p53 (mouse), homozygous knockout] (4), pancreas (6), spleen (5, 6), testis (6)




References

1

Parker BL, et al. (2015) Targeted phosphoproteomics of insulin signaling using data-independent acquisition mass spectrometry. Sci Signal 8, rs6
26060331   Curated Info

2

Wu X, et al. (2012) Investigation of receptor interacting protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomics. Mol Cell Proteomics 11, 1640-51
22942356   Curated Info

3

Grimsrud PA, et al. (2012) A quantitative map of the liver mitochondrial phosphoproteome reveals posttranslational control of ketogenesis. Cell Metab 16, 672-83
23140645   Curated Info

4

Hsu PP, et al. (2011) The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. Science 332, 1317-22
21659604   Curated Info

5

Manes NP, et al. (2011) Discovery of mouse spleen signaling responses to anthrax using label-free quantitative phosphoproteomics via mass spectrometry. Mol Cell Proteomics 10, M110.000927
21189417   Curated Info

6

Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89
21183079   Curated Info

7

Wiƛniewski JR, et al. (2010) Brain phosphoproteome obtained by a FASP-based method reveals plasma membrane protein topology. J Proteome Res 9, 3280-9
20415495   Curated Info

8

Tweedie-Cullen RY, Reck JM, Mansuy IM (2009) Comprehensive mapping of post-translational modifications on synaptic, nuclear, and histone proteins in the adult mouse brain. J Proteome Res 8, 4966-82
19737024   Curated Info

9

Munton RP, et al. (2007) Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Mol Cell Proteomics 6, 283-93
17114649   Curated Info

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