Ser978
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Phosphorylation Site Page:
Ser978 - GM130 (mouse)

Site Information
RERPGLGsNPCIPFF   SwissProt Entrez-Gene
Predicted information:  Scansite
Orthologous residues: GM130 (human): S981, GM130 iso3 (human): (‑), GM130 iso2 (mouse): (S946), GM130 iso3 (mouse): (S1005), GM130 (rat): (S977)
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 4769569

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (1, 3, 4, 5, 6)
Relevant cell line - cell type - tissue: '3T3-L1, differentiated' (adipocyte) (1, 3), 'fat, brown'-'fat, brown' (6), brain (4), kidney (6), lung (6), MEF (fibroblast) [TSC2 (mouse), homozygous knockout] (5), spleen (6), testis (6)




References

1

Parker BL, et al. (2015) Targeted phosphoproteomics of insulin signaling using data-independent acquisition mass spectrometry. Sci Signal 8, rs6
26060331   Curated Info

2

Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 13, 1690-704
24719451   Curated Info

3

Humphrey SJ, et al. (2013) Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2. Cell Metab 17, 1009-20
23684622   Curated Info

4

Trinidad JC, et al. (2012) Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse. Mol Cell Proteomics 11, 215-29
22645316   Curated Info

5

Yu Y, et al. (2011) Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. Science 332, 1322-6
21659605   Curated Info

6

Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89
21183079   Curated Info

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