Phosphorylation Site Page:
In vivo Characterization
Methods used to characterize site
mass spectrometry ( 1, 3, 5)
Disease tissue studied:
cervical cancer ( 5), cervical adenocarcinoma ( 5)
Relevant cell line - cell type - tissue:
HeLa (cervical) ( 1, 3), HeLa S3 (cervical) ( 5), K562 (erythroid) ( 3)
Sharma K, et al. (2014) Ultradeep human phosphoproteome reveals a distinct regulatory nature of Tyr and Ser/Thr-based signaling.
Cell Rep 8, 1583-94
Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels.
Mol Cell Proteomics 13, 1690-704
Zhou H, et al. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome.
J Proteome Res 12, 260-71
Rigbolt KT, et al. (2011) System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
Sci Signal 4, rs3
Olsen JV, et al. (2010) Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
Sci Signal 3, ra3