Ser740
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
HomeAbout PhosphoSiteUsing PhosphoSiteCuration ProcessContact
logos LINCs Logo Mt Sinai Logo NIH Logo NCI Logo
Phosphorylation Site Page:
Ser740 - CD44 (mouse)

Site Information
SELNGEAsKSQEMVH   SwissProt Entrez-Gene
Predicted information:  Scansite
Orthologous residues: CD44 (human): S704, CD44 iso2 (mouse): S325, CD44 iso10 (human): (S455), CD44 iso12 (human): (S323), CD44 iso30 (human): (S704), CD44 (rat): (S465)
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 465561

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (1, 2, 3, 4)
Disease tissue studied: leukemia (2), acute myelogenous leukemia (2), melanoma skin cancer (3)
Relevant cell line - cell type - tissue: blood (2), macrophage-peritoneum (1), macrophage-peritoneum [RIP3 (mouse), homozygous knockout] (1), skin [mGluR1 (mouse), transgenic, TG mutant mice] (3)




References

1

Wu X, et al. (2012) Investigation of receptor interacting protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomics. Mol Cell Proteomics 11, 1640-51
22942356   Curated Info

2

Trost M, et al. (2012) Posttranslational regulation of self-renewal capacity: insights from proteome and phosphoproteome analyses of stem cell leukemia. Blood 120, e17-27
22802335   Curated Info

3

Zanivan S, et al. (2008) Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry. J Proteome Res 7, 5314-26
19367708   Curated Info

4

(2008) CST Curation Set: 4770; Year: 2008; Biosample/Treatment: cell line, Dana Farber-S3/untreated; Disease: -; SILAC: -; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-RXX(s/t)(phosphorylation) Antibody Used to Purify Peptides prior to MS2: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS*/T*) Immunoaffinity Beads Cat#: 1978
Curated Info

Home  |  Curator Login With enhanced literature mining using Linguamatics I2E I2E Logo Produced by 3rd Millennium  |  Design by Digizyme
©2003-2013 Cell Signaling Technology, Inc.