Phosphorylation Site Page:
In vivo Characterization
Methods used to characterize site
mass spectrometry ( 1, 2, 3)
Disease tissue studied:
breast cancer ( 2), HER2 positive breast cancer ( 1), luminal A breast cancer ( 1), luminal B breast cancer ( 1), breast cancer, triple negative ( 1)
Relevant cell line - cell type - tissue:
breast ( 1), HeLa (cervical) ( 3), MCF10A1 (epithelial) ( 2), MCF10AT1K (epithelial) ( 2), MCF10CA1a (epithelial) ( 2), MCF10CA1h (epithelial) ( 2)
Mertins P, et al. (2016) Proteogenomics connects somatic mutations to signalling in breast cancer.
Nature 534, 55-62
Chen Y, et al. (2007) Differential expression of novel tyrosine kinase substrates during breast cancer development.
Mol Cell Proteomics 6, 2072-87
Yu LR, et al. (2007) Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.
J Proteome Res 6, 4150-62