Ser382
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Phosphorylation Site Page:
Ser382 - YAP1 (mouse)

Site Information
TYHSRDEsTDSGLSM   SwissProt Entrez-Gene
Predicted information:  Scansite
Orthologous residues: YAP1 (human): S397, YAP1 iso2 (human): S381, YAP1 (sheep): (S296), YAP1 iso3 (human): (S347), YAP1 iso3 (rat): (‑), YAP1 (rat): (S363)
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3190672

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (2, 3, 5), phospho-antibody (1), western blotting (1)
Relevant cell line - cell type - tissue: '3T3-L1, differentiated' (adipocyte) (3), Hepa 1-6 (epithelial) (5), liver (2)

Controlled by
Putative upstream kinases: NDR1 (mouse) (1), NDR2 (mouse) (1)
Treatments: insulin (3)



References

1

Zhang L, et al. (2015) NDR Functions as a Physiological YAP1 Kinase in the Intestinal Epithelium. Curr Biol 25, 296-305
25601544   Curated Info

2

Wilson-Grady JT, Haas W, Gygi SP (2013) Quantitative comparison of the fasted and re-fed mouse liver phosphoproteomes using lower pH reductive dimethylation. Methods 61, 277-86
23567750   Curated Info

3

Humphrey SJ, et al. (2013) Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2. Cell Metab 17, 1009-20
23684622   Curated Info

4

Kim M, et al. (2013) cAMP/PKA signalling reinforces the LATS-YAP pathway to fully suppress YAP in response to actin cytoskeletal changes. EMBO J 32, 1543-55
23644383   Curated Info

5

Pan C, Gnad F, Olsen JV, Mann M (2008) Quantitative phosphoproteome analysis of a mouse liver cell line reveals specificity of phosphatase inhibitors. Proteomics 8, 4534-46
18846507   Curated Info

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