Thr178
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Phosphorylation Site Page:
Thr178 - H2AFY (mouse)

Site Information
ADSTTEGtPTDGFTV   SwissProt Entrez-Gene
Predicted information:  Scansite
Orthologous residues: H2AFY (human): T178, H2AFY (rat): (A177)
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3176083

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (1, 3, 4, 5, 6)
Relevant cell line - cell type - tissue: 'fat, brown'-'fat, brown' (5), brain (5), heart (5), kidney (5), liver (1, 4, 5), liver [leptin (mouse), homozygous knockout] (4), lung (5), macrophage-bone marrow (6), macrophage-bone marrow [MKP-1 (mouse), homozygous knockout] (6), macrophage-peritoneum [RIP3 (mouse), homozygous knockout] (3), pancreas (5), spleen (5)




References

1

Wilson-Grady JT, Haas W, Gygi SP (2013) Quantitative comparison of the fasted and re-fed mouse liver phosphoproteomes using lower pH reductive dimethylation. Methods 61, 277-86
23567750   Curated Info

2

Humphrey SJ, et al. (2013) Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2. Cell Metab 17, 1009-20
23684622   Curated Info

3

Wu X, et al. (2012) Investigation of receptor interacting protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomics. Mol Cell Proteomics 11, 1640-51
22942356   Curated Info

4

Grimsrud PA, et al. (2012) A quantitative map of the liver mitochondrial phosphoproteome reveals posttranslational control of ketogenesis. Cell Metab 16, 672-83
23140645   Curated Info

5

Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89
21183079   Curated Info

6

Weintz G, et al. (2010) The phosphoproteome of toll-like receptor-activated macrophages. Mol Syst Biol 6, 371
20531401   Curated Info

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