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Phosphorylation Site Page:
Ser1325 - ITGB4 (human)

Site Information
tQPKRPMsIPIIPDI   SwissProt Entrez-Gene
Predicted information:  Scansite
Orthologous residues: ITGB4 (rat): (S1327), ITGB4 iso2 (human): (S1325), ITGB4 iso2 (mouse): (S1327), ITGB4 iso3 (human): (S1325), ITGB4 (mouse): (S1327), ITGB4 iso3 (mouse): (S1327)
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3103700

In vivo Characterization
Methods used to characterize site in vivo: mutation of modification site (1)
Disease tissue studied: PA-JEB (1)
Relevant cell line - cell type - tissue: PA-JEB (keratinocyte) (1)

Downstream Regulation
Effects of modification on ITGB4: molecular association, regulation (1)
Induce interaction with: Plectin-1 (human) (1)



Litjens SH, et al. (2005) Modeling and experimental validation of the binary complex of the plectin actin-binding domain and the first pair of fibronectin type III (FNIII) domains of the beta4 integrin. J Biol Chem 280, 22270-7
15817481   Curated Info

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