Tyr732
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Phosphorylation Site Page:
Tyr732 - Kit (mouse)

Site Information
DMKPGVSyVVPTKTD   SwissProt Entrez-Gene
Predicted information:  Scansite
Orthologous residues: Kit (human): Y730, Kit (rat): (Y731)
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 454941
Additional spectra:  1 CST

In vivo Characterization
Methods used to characterize site in vivo: flow cytometry (3), immunoprecipitation (3), mass spectrometry (1, 2), mutation of modification site (3), phospho-antibody (3), western blotting (3)
Relevant cell line - cell type - tissue: 32D (myeloid) (3)


Downstream Regulation
Effects of modification on Kit: activity, induced (3), phosphorylation (3)
Effects of modification on biological processes: cell cycle regulation (3), cell growth, altered (3)


References

1

(2006) CST Curation Set: 1516; Year: 2006; Biosample/Treatment: cell line, Thom/serum starved; Disease: -; SILAC: -; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

2

(2006) CST Curation Set: 1517; Year: 2006; Biosample/Treatment: cell line, Thom/serum starved; Disease: -; SILAC: -; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

3

Gommerman JL, et al. (2000) Differential stimulation of c-Kit mutants by membrane-bound and soluble Steel Factor correlates with leukemic potential. Blood 96, 3734-42
11090054   Curated Info

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