Phosphorylation Site Page:
In vivo Characterization
Methods used to characterize site
mass spectrometry ( 1, 2, 3, 4)
Disease tissue studied:
melanoma skin cancer ( 1)
Relevant cell line - cell type - tissue:
HeLa (cervical) ( 3, 4), Jurkat (T lymphocyte) ( 2), WM239A (epidermal) ( 1)
Stuart SA, et al. (2015) A Phosphoproteomic Comparison of B-RAFV600E and MKK1/2 Inhibitors in Melanoma Cells.
Mol Cell Proteomics 14, 1599-615
Mertins P, et al. (2013) Integrated proteomic analysis of post-translational modifications by serial enrichment.
Nat Methods 10, 634-7
Kettenbach AN, et al. (2011) Quantitative phosphoproteomics identifies substrates and functional modules of aurora and polo-like kinase activities in mitotic cells.
Sci Signal 4, rs5
Hegemann B, et al. (2011) Systematic phosphorylation analysis of human mitotic protein complexes.
Sci Signal 4, rs12