Ser953
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Phosphorylation Site Page:
Ser953 - Nogo (mouse)

Site Information
EAEEKLPsDTEKEDR   SwissProt Entrez-Gene
Predicted information:  Scansite
Orthologous residues: Nogo (rat): S954, Nogo iso6 (human): (S777), Nogo iso4 (human): (S751), Nogo iso5 (human): (‑), Nogo iso6 (mouse): (‑), Nogo iso5 (mouse): (‑), Nogo iso3 (human): (‑), Nogo iso2 (rat): (‑), Nogo iso2 (human): (‑), Nogo (human): (S983), Nogo iso4 (mouse): (S953)
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 15721612

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (1, 2, 3, 4, 5, 6, 7)
Disease tissue studied: leukemia (4), acute myelogenous leukemia (4), neuroblastoma (5)
Relevant cell line - cell type - tissue: '3T3-L1, differentiated' (adipocyte) (1, 2), blood (4), brain (7), macrophage-bone marrow (6), macrophage-bone marrow [MKP-1 (mouse), homozygous knockout] (6), macrophage-peritoneum [RIP3 (mouse), homozygous knockout] (3), N1E-115 (neuron) (5)

Controlled by
Treatments: LPA (5)



References

1

Parker BL, et al. (2015) Targeted phosphoproteomics of insulin signaling using data-independent acquisition mass spectrometry. Sci Signal 8, rs6
26060331   Curated Info

2

Humphrey SJ, et al. (2013) Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2. Cell Metab 17, 1009-20
23684622   Curated Info

3

Wu X, et al. (2012) Investigation of receptor interacting protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomics. Mol Cell Proteomics 11, 1640-51
22942356   Curated Info

4

Trost M, et al. (2012) Posttranslational regulation of self-renewal capacity: insights from proteome and phosphoproteome analyses of stem cell leukemia. Blood 120, e17-27
22802335   Curated Info

5

Wang Y, et al. (2011) Spatial phosphoprotein profiling reveals a compartmentalized extracellular signal-regulated kinase switch governing neurite growth and retraction. J Biol Chem 286, 18190-201
21454597   Curated Info

6

Weintz G, et al. (2010) The phosphoproteome of toll-like receptor-activated macrophages. Mol Syst Biol 6, 371
20531401   Curated Info

7

Wiƛniewski JR, et al. (2010) Brain phosphoproteome obtained by a FASP-based method reveals plasma membrane protein topology. J Proteome Res 9, 3280-9
20415495   Curated Info

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