Ser619
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Phosphorylation Site Page:
Ser619 - TCF8 (mouse)

Site Information
AGQIPGQsPDPPSPG   SwissProt Entrez-Gene
Predicted information:  Scansite
Orthologous residues: TCF8 (human): S641, TCF8 iso2 (human): (S642), TCF8 (rat): (S619)
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 14581500

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (1, 2, 3)
Relevant cell line - cell type - tissue: '3T3-L1, differentiated' (adipocyte) (2), 32Dcl3 (myeloid) (3), 32Dcl3 (myeloid) [FLT3 (mouse), transfection, chimera with human FLT3-ITD mutant (corresponding to wild type P36888 ~aa 525-695 ETILLNS...IFEYCC)] (3), liver (1)




References

1

Wilson-Grady JT, Haas W, Gygi SP (2013) Quantitative comparison of the fasted and re-fed mouse liver phosphoproteomes using lower pH reductive dimethylation. Methods 61, 277-86
23567750   Curated Info

2

Humphrey SJ, et al. (2013) Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2. Cell Metab 17, 1009-20
23684622   Curated Info

3

Choudhary C, et al. (2009) Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes. Mol Cell 36, 326-39
19854140   Curated Info

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