Tyr88
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Phosphorylation Site Page:
Tyr88 - PTP-PEST (human)

Site Information
TPSQDSDyINANFIK   SwissProt Entrez-Gene
Predicted information:  Scansite
Orthologous residues: PTP‑PEST iso2 (human): (‑), PTP‑PEST iso3 (human): (‑), PTP‑PEST (rat): (Y88), PTP‑PEST (mouse): (Y88)
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 10847376

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (1, 2, 3, 4)
Disease tissue studied: kidney cancer (3), liver cancer (4), hepatocellular carcinoma (4), lung cancer (2)
Relevant cell line - cell type - tissue: hepatocyte-liver (4), kidney (3), lung (2), MDA-MB231 (breast cell) (1), MDA-MB231 (breast cell) [Syk (human), transfection, Tet-reponsive Syk-inducible system] (1)




References

1

Iliuk AB, et al. (2010) In-depth analyses of kinase-dependent tyrosine phosphoproteomes based on metal ion-functionalized soluble nanopolymers. Mol Cell Proteomics 9, 2162-72
20562096   Curated Info

2

Hu Y (2010) CST Curation Set: 8947; Year: 2010; Biosample/Treatment: tissue, lung/untreated; Disease: lung cancer; SILAC: -; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

3

Tucker M (2009) CST Curation Set: 7686; Year: 2009; Biosample/Treatment: tissue, kidney/untreated; Disease: kidney cancer; SILAC: -; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

4

Gu T (2009) CST Curation Set: 6599; Year: 2009; Biosample/Treatment: liver, hepatocyte/untreated; Disease: liver cancer; SILAC: -; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

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