Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
HomeAbout PhosphoSiteUsing PhosphoSiteprivacy & cookiesCuration ProcessContact
logos LINCs Logo Mt Sinai Logo NIH Logo NCI Logo
Protein Page:
HLAC (human)

Overview
HLAC Involved in the presentation of foreign antigens to the immune system. Belongs to the MHC class I family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 6p21.3
Cellular Component: cell surface; early endosome membrane; endoplasmic reticulum; Golgi apparatus; Golgi membrane; MHC class I protein complex; phagocytic vesicle membrane; plasma membrane
Molecular Function: antigen binding; peptide antigen binding
Biological Process: antigen processing and presentation; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; antigen processing and presentation of peptide antigen via MHC class I; regulation of immune response
Disease: Human Immunodeficiency Virus Type 1, Susceptibility To; Psoriasis 1, Susceptibility To
Reference #:  P30501 (UniProtKB)
Alt. Names/Synonyms: 1C02; class I MHC antigen HLA-B heavy chain; D6S204; FLJ27082; HLA class I antigen; HLA class I heavy chain; HLA class I histocompatibility antigen, C alpha chain; HLA class I histocompatibility antigen, Cw-1 alpha chain; HLA class I histocompatibility antigen, Cw-12 alpha chain; HLA class I histocompatibility antigen, Cw-14 alpha chain; HLA class I histocompatibility antigen, Cw-16 alpha chain; HLA class I histocompatibility antigen, Cw-17 alpha chain; HLA class I histocompatibility antigen, Cw-2 alpha chain; HLA class I histocompatibility antigen, Cw-4 alpha chain; HLA class I histocompatibility antigen, Cw-6 alpha chain; HLA class I histocompatibility antigen, Cw-7 alpha chain; HLA class I histocompatibility antigen, Cw-8 alpha chain; HLA-C; HLA-C (Cw*1201); HLA-Cw; HLA-Cw*050x; HLA-Cw12; HLA-JY3; HLAC; HLC-C; human leukocyte antigen-C alpha chain; leucocyte antigen C; leucocyte antigen Cw; leukocyte antigen-C alpha chain; major histocompatibility antigen HLA-C; major histocompatibility complex, class I, C; MHC class I antigen Cw*1; MHC class I antigen Cw*12; MHC class I antigen Cw*14; MHC class I antigen Cw*16; MHC class I antigen Cw*17; MHC class I antigen Cw*2; MHC class I antigen Cw*4; MHC class I antigen Cw*6; MHC class I antigen Cw*7; MHC class I antigen Cw*8; MHC class I antigen heavy chain HLA-C; MHC class I antigen HLA-C; MHC class I HLA-C; MHC class I HLA-Cw*0803; MHC class I protein HLA-C heavy chain; PSORS1
Gene Symbols: HLA-C
Molecular weight: 41,095 Da
Basal Isoelectric point: 5.76  Predict pI for various phosphorylation states
Select Structure to View Below

HLAC

Protein Structure Not Found.
Download PyMol Script
Download ChimeraX Script


STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Scansite  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene