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BIK
accelerates programmed cell death. Binding to the apoptosis repressors Bcl-xL, Bcl-2, or BHRF1 (the Epstein-Barr virus homolog of Bcl-2) suppresses its death-promoting activity. Contains 1 Bcl-2 homology 3 (BH3) domain. Does not interact with Bax. Note: This description may include information from UniProtKB.
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| Protein type: Apoptosis; Membrane protein, integral; Mitochondrial |
| Chromosomal Location of Human Ortholog: 22q13.2 |
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Molecular Function: protein binding
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Biological Process: apoptosis; male gonad development; positive regulation of protein homooligomerization
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Reference #:
Q13323
(UniProtKB)
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Alt. Names/Synonyms: Apoptosis inducer NBK; apoptosis-inducing NBK; Bcl-2-interacting killer; BCL2-interacting killer (apoptosis-inducing); BIK; BIP1; BP4; NBK
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Gene Symbols: BIK
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Molecular weight:
18,016 Da
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Basal Isoelectric point:
4.21
Predict pI for various phosphorylation states
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Protein-Specific Antibodies or siRNAs from Cell Signaling Technology®
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