a multi-pass membrane protein. A multidrug resistance member of the ABC transporter family that confers resistance to anticancer drugs. A multi-pass membrane protein. Exports sphingosine-1-phosphate (S1P), a potent inflammatory mediator, from mast cells during mast cell-mediated immune responses. Nine alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ABC family
Cellular Component: basolateral plasma membrane; cytoplasm; integral to plasma membrane; membrane; plasma membrane
Alt. Names/Synonyms: Abcc1; Abcc1a; Abcc1b; ATP-binding cassette sub-family C member 1; ATP-binding cassette, sub-family C (CFTR/MRP), member 1; ATP-binding cassette, sub-family C (CFTR/MRP), member 1a; ATP-binding cassette, sub-family C (CFTR/MRP), member 1b; Leukotriene C(4) transporter; LTC4 transporter; Mdrap; Mrp; Mrp1; Multidrug resistance-associated protein 1; multiple drug resistance-associated protein