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Protein Page:
Arg (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitylation
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
Arg a cytoplasmic tyrosine kinase of the Abl family. Expressed at the highest levels in mature B cells. Promotes catalase degradation in the oxidative stress response. Localizes to dynamic actin structures and may regulate cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. 4 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Protein kinase, TK; Oncoprotein; Protein kinase, tyrosine (non-receptor); EC 2.7.10.2; Kinase, protein; TK group; Abl family
Chromosomal Location of Human Ortholog: 1q25.2
Cellular Component: actin cytoskeleton; cytosol; extrinsic to internal side of plasma membrane
Molecular Function: actin filament binding; actin monomer binding; magnesium ion binding; manganese ion binding; non-membrane spanning protein tyrosine kinase activity; protein binding; protein kinase activity; protein-tyrosine kinase activity; receptor binding
Biological Process: elevation of cytosolic calcium ion concentration; innate immune response; peptidyl-tyrosine phosphorylation; positive regulation of oxidoreductase activity; protein modification process; regulation of autophagy; regulation of cell adhesion; regulation of cell proliferation; regulation of endocytosis; signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway
Reference #:  P42684 (UniProtKB)
Alt. Names/Synonyms: Abelson murine leukemia viral (v-abl) oncogene homolog 2; Abelson murine leukemia viral oncogene homolog 2; Abelson-related gene protein; ABL2; ABLL; ARG; arg tyrosine kinase; FLJ22224; FLJ31718; FLJ41441; Tyrosine-protein kinase ABL2; Tyrosine-protein kinase ARG; v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)
Gene Symbols: ABL2
Molecular weight: 128,343 Da
Basal Isoelectric point: 8.31  Predict pI for various phosphorylation states
CST Pathways:  Tyrosine Kinases & Substrates
Select Structure to View Below

Arg

Protein Structure Not Found.
Download PyMol Script
Download ChimeraX Script

Substrate Sequence Logo
Sequence Logo

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Sites Implicated In
protein degradation: Y439‑p
protein stabilization: Y261‑p
ubiquitination: Y261‑p

Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment



 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

► Hide Isoforms
 
0 1 S31‑p GSSAARPsGRRRDPA
0 2 T68‑p DGFEGDKtGGssPEA
0 3 S71‑p EGDKtGGssPEALHR
0 3 S72‑p GDKtGGssPEALHRP
0 1 Y80 PEALHRPYGCDVEPQ
0 1 P86 PYGCDVEPQALNEAI
0 6 S96‑p LNEAIRWssKENLLG
0 15 S97‑p NEAIRWssKENLLGA
0 10 Y116‑p PNLFVALyDFVAsGD
0 5 S121‑p ALyDFVAsGDNTLSI
1 0 Y139‑p EKLRVLGyNQNGEWS
1 219 Y161‑p QGWVPSNyITPVNSL
0 212 Y174‑p SLEKHSWyHGPVSRS
0 1 S194‑p LSSLINGsFLVRESE
0 2 S203‑p LVRESESsPGQLsIS
0 3 S208‑p ESsPGQLsISLRyEG
0 13 Y213‑p QLsISLRyEGRVyHY
0 106 Y218‑p LRyEGRVyHYRINTT
0 5 Y231‑p TTADGKVyVTAESRF
1 0 Y261‑p GLVTTLHyPAPKCNK
2 5 Y272‑p KCNKPTVyGVsPIHD
0 2 S275‑p KPTVyGVsPIHDKWE
0 4 Y303‑p GGQYGEVyVGVWKKy
0 59 Y310‑p yVGVWKKySLTVAVK
0 2 K320‑ac TVAVKTLkEDTMEVE
0 1 K331‑ub MEVEEFLkEAAVMKE
0 72 T438‑p SRLMTGDtytAHAGA
3 1662 Y439‑p RLMTGDtytAHAGAK
0 476 T440‑p LMTGDtytAHAGAKF
0 1 T452‑p AKFPIKWtAPESLAy
0 1 Y459‑p tAPESLAyNTFSIKS
0 43 Y515‑p EGCPPKVyELMRACW
1 12 Y568‑p SSSSVVPyLPRLPIL
0 1 R571 SVVPyLPRLPILPsK
0 1 S577‑p PRLPILPsKTRtLKK
0 1 T581‑p ILPsKTRtLKKQVEN
0 5 S602‑p AQDATENsASSLAPG
0 1 S617‑p FIRGAQAssGsPALP
0 3 S618‑p IRGAQAssGsPALPR
0 30 S620‑p GAQAssGsPALPRKQ
0 49 S631‑p PRKQRDKsPssLLED
0 7 S633‑p KQRDKsPssLLEDAK
0 2 S634‑p QRDKsPssLLEDAKE
0 27 S655‑p RKGGFFSsFMKkRNA
0 4 K659‑ac FFSsFMKkRNAPtPP
0 2 T664‑p MKkRNAPtPPkRSSs
0 1 K667‑m2 RNAPtPPkRSSsFRE
0 13 S671‑p tPPkRSSsFREMENQ
1 5 Y683 ENQPHKKYELTGNFS
0 44 Y718‑p NLVPPKCyGGSFAQR
0 18 T753‑p SGITGFFtPRLIKKT
0 2 S781‑p TSKPFPRsNstSSMS
0 11 S783‑p KPFPRsNstSSMSSG
0 3 T784‑p PFPRsNstSSMSSGL
0 2 S785 FPRsNstSSMSSGLP
0 3 T815‑p SKLQLERtVstssQP
0 65 S817‑p LQLERtVstssQPEE
0 5 T818‑p QLERtVstssQPEEN
0 3 S819‑p LERtVstssQPEENV
0 60 S820‑p ERtVstssQPEENVD
0 2 T864‑p ATALPLRtPsGDLAI
0 2 S866‑p ALPLRtPsGDLAITE
0 7 S915‑p GEQPGWPsPAKAAPV
0 1 T926 AAPVLPTTHNHKVPV
0 26 S936‑p HKVPVLIsPtLKHTP
0 9 T938‑p VPVLIsPtLKHTPAD
0 1 S969‑p SEHQVTSsGDKDRPR
0 1 K981‑ac RPRRVKPkCAPPPPP
0 1 S1051‑p PQVPLPTsSIsPAKM
0 4 S1054‑p PLPTsSIsPAKMANG
0 1 S1107‑p LTEPVPNsQLVDtGH
0 1 T1112‑p PNsQLVDtGHQLLDY
  Arg iso2  
- gap
- gap
- gap
- gap
Y44 TEALHRPYGCDVEPQ
P50 PYGCDVEPQALNEAI
S60 LNEAIRWSSKENLLG
S61 NEAIRWSSKENLLGA
Y80 PNLFVALYDFVASGD
S85 ALYDFVASGDNTLSI
Y103 EKLRVLGYNQNGEWS
Y125 QGWVPSNYITPVNSL
Y138 SLEKHSWYHGPVSRS
S158 LSSLINGSFLVRESE
S167 LVRESESSPGQLSIS
S172 ESSPGQLSISLRYEG
Y177 QLSISLRYEGRVYHY
Y182 LRYEGRVYHYRINTT
Y195 TTADGKVYVTAESRF
Y225 GLVTTLHYPAPKCNK
Y236 KCNKPTVYGVSPIHD
S239 KPTVYGVSPIHDKWE
Y267 GGQYGEVYVGVWKKY
Y274 YVGVWKKYSLTVAVK
K284 TVAVKTLKEDTMEVE
K295 MEVEEFLKEAAVMKE
T402 SRLMTGDTYTAHAGA
Y403 RLMTGDTYTAHAGAK
T404 LMTGDTYTAHAGAKF
T416 AKFPIKWTAPESLAY
Y423 TAPESLAYNTFSIKS
Y479 EGCPPKVYELMRACW
Y532 SSSSVVPYLPRLPIL
R535 SVVPYLPRLPILPSK
S541 PRLPILPSKTRTLKK
T545 ILPSKTRTLKKQVEN
S566 AQDATENSASSLAPG
S581 FIRGAQASSGSPALP
S582 IRGAQASSGSPALPR
S584 GAQASSGSPALPRKQ
S595 PRKQRDKSPSSLLED
S597 KQRDKSPSSLLEDAK
S598 QRDKSPSSLLEDAKE
S619 RKGGFFSSFMKKRNA
K623 FFSSFMKKRNAPTPP
T628 MKKRNAPTPPKRSSS
K631 RNAPTPPKRSSSFRE
S635 TPPKRSSSFREMENQ
Y647 ENQPHKKYELTGNFS
Y682 NLVPPKCYGGSFAQR
T717 SGITGFFTPRLIKKT
S745 TSKPFPRSNSTSSMS
S747 KPFPRSNSTSSMSSG
T748 PFPRSNSTSSMSSGL
S749 FPRSNSTSSMSSGLP
T779 SKLQLERTVSTSSQP
S781 LQLERTVSTSSQPEE
T782 QLERTVSTSSQPEEN
S783 LERTVSTSSQPEENV
S784 ERTVSTSSQPEENVD
T828 ATALPLRTPSGDLAI
S830 ALPLRTPSGDLAITE
S879 GEQPGWPSPAKAAPV
T890 AAPVLPTTHNHKVPV
S900 HKVPVLISPTLKHTP
T902 VPVLISPTLKHTPAD
S933 SEHQVTSSGDKDRPR
K945 RPRRVKPKCAPPPPP
S1015 PQVPLPTSSISPAKM
S1018 PLPTSSISPAKMANG
S1071 LTEPVPNSQLVDTGH
T1076 PNSQLVDTGHQLLDY
  Arg iso4  
- gap
- gap
- gap
- gap
Y45 TEALHRPYGCDVEPQ
P51 PYGCDVEPQALNEAI
S61 LNEAIRWSSKENLLG
S62 NEAIRWSSKENLLGA
Y81 PNLFVALYDFVASGD
S86 ALYDFVASGDNTLSI
Y104 EKLRVLGYNQNGEWS
Y126 QGWVPSNYITPVNSL
Y139 SLEKHSWYHGPVSRS
S159 LSSLINGSFLVRESE
S168 LVRESESSPGQLSIS
S173 ESSPGQLSISLRYEG
Y178 QLSISLRYEGRVYHY
Y183 LRYEGRVYHYRINTT
Y196 TTADGKVYVTAESRF
Y226 GLVTTLHYPAPKCNK
Y237 KCNKPTVYGVSPIHD
S240 KPTVYGVSPIHDKWE
Y268 GGQYGEVYVGVWKKY
Y275 YVGVWKKYSLTVAVK
K285 TVAVKTLKEDTMEVE
K296 MEVEEFLKEAAVMKE
T403 SRLMTGDTyTAHAGA
Y404‑p RLMTGDTyTAHAGAK
T405 LMTGDTyTAHAGAKF
T417 AKFPIKWTAPESLAY
Y424 TAPESLAYNTFSIKS
Y480 EGCPPKVYELMRACW
Y533 SSSSVVPYLPRLPIL
R536 SVVPYLPRLPILPSK
S542 PRLPILPSKTRTLKK
T546 ILPSKTRTLKKQVEN
S567 AQDATENSASSLAPG
S582 FIRGAQASSGSPALP
S583 IRGAQASSGSPALPR
S585 GAQASSGSPALPRKQ
S596 PRKQRDKSPSSLLED
S598 KQRDKSPSSLLEDAK
S599 QRDKSPSSLLEDAKE
S620 RKGGFFSSFMKKRNA
K624 FFSSFMKKRNAPTPP
T629 MKKRNAPTPPKRSSS
K632 RNAPTPPKRSSSFRE
S636 TPPKRSSSFREMENQ
Y648‑p ENQPHKKyELTGLPE
- gap
- gap
- gap
- gap
- gap
- gap
T677 SKLQLERTVSTSSQP
S679 LQLERTVSTSSQPEE
T680 QLERTVSTSSQPEEN
S681 LERTVSTSSQPEENV
S682 ERTVSTSSQPEENVD
T726 ATALPLRTPSGDLAI
S728 ALPLRTPSGDLAITE
S777 GEQPGWPSPAKAAPV
T788 AAPVLPTTHNHKVPV
S798 HKVPVLISPTLKHTP
T800 VPVLISPTLKHTPAD
S831 SEHQVTSSGDKDRPR
K843 RPRRVKPKCAPPPPP
S913 PQVPLPTSSISPAKM
S916 PLPTSSISPAKMANG
S969 LTEPVPNSQLVDTGH
T974 PNSQLVDTGHQLLDY
  Arg iso6  
S31 GSSAARPSGRRRDPA
- gap
- gap
- gap
Y59‑p HEALHRPyGCDVEPQ
P65 PyGCDVEPQALNEAI
S75 LNEAIRWSSKENLLG
S76 NEAIRWSSKENLLGA
Y95 PNLFVALYDFVASGD
S100 ALYDFVASGDNTLSI
Y118 EKLRVLGYNQNGEWS
Y140 QGWVPSNYITPVNSL
Y153 SLEKHSWYHGPVSRS
S173 LSSLINGSFLVRESE
S182 LVRESESSPGQLSIS
S187 ESSPGQLSISLRYEG
Y192 QLSISLRYEGRVYHY
Y197 LRYEGRVYHYRINTT
Y210 TTADGKVYVTAESRF
Y240 GLVTTLHYPAPKCNK
Y251 KCNKPTVYGVSPIHD
S254 KPTVYGVSPIHDKWE
Y282 GGQYGEVYVGVWKKY
Y289 YVGVWKKYSLTVAVK
K299 TVAVKTLKEDTMEVE
K310 MEVEEFLKEAAVMKE
T417 SRLMTGDTYTAHAGA
Y418 RLMTGDTYTAHAGAK
T419 LMTGDTYTAHAGAKF
T431 AKFPIKWTAPESLAY
Y438 TAPESLAYNTFSIKS
Y494 EGCPPKVYELMRACW
Y547 SSSSVVPYLPRLPIL
R550 SVVPYLPRLPILPSK
S556 PRLPILPSKTRTLKK
T560 ILPSKTRTLKKQVEN
S581 AQDATENSASSLAPG
S596 FIRGAQASSGSPALP
S597 IRGAQASSGSPALPR
S599 GAQASSGSPALPRKQ
S610 PRKQRDKSPSSLLED
S612 KQRDKSPSSLLEDAK
S613 QRDKSPSSLLEDAKE
S634 RKGGFFSSFMKKRNA
K638 FFSSFMKKRNAPTPP
T643 MKKRNAPTPPKRSSS
K646 RNAPTPPKRSSSFRE
S650 TPPKRSSSFREMENQ
Y662 ENQPHKKYELTGNFS
Y697 NLVPPKCYGGSFAQR
T732 SGITGFFTPRLIKKT
S760 TSKPFPRSNSTSSMS
S762 KPFPRSNSTSSMSSG
T763 PFPRSNSTSSMSSGL
S764 FPRSNSTSSMSSGLP
T794 SKLQLERTVSTSSQP
S796 LQLERTVSTSSQPEE
T797 QLERTVSTSSQPEEN
S798 LERTVSTSSQPEENV
S799 ERTVSTSSQPEENVD
T843 ATALPLRTPSGDLAI
S845 ALPLRTPSGDLAITE
S894 GEQPGWPSPAKAAPV
T905 AAPVLPTTHNHKVPV
S915 HKVPVLISPTLKHTP
T917 VPVLISPTLKHTPAD
S948 SEHQVTSSGDKDRPR
K960 RPRRVKPKCAPPPPP
S1030 PQVPLPTSSISPAKM
S1033 PLPTSSISPAKMANG
S1086 LTEPVPNSQLVDTGH
T1091 PNSQLVDTGHQLLDY
  Arg iso10  
- gap
T53 DGFEGDKTGGSSPEA
S56 EGDKTGGSSPEALHR
S57 GDKTGGSSPEALHRP
Y65 PEALHRPYGCDVEPQ
P71 PYGCDVEPQALNEAI
S81 LNEAIRWSSKENLLG
S82 NEAIRWSSKENLLGA
Y101 PNLFVALYDFVASGD
S106 ALYDFVASGDNTLSI
Y124 EKLRVLGYNQNGEWS
Y146 QGWVPSNYITPVNSL
Y159 SLEKHSWYHGPVSRS
S179 LSSLINGSFLVRESE
S188 LVRESESSPGQLSIS
S193 ESSPGQLSISLRYEG
Y198 QLSISLRYEGRVYHY
Y203 LRYEGRVYHYRINTT
Y216 TTADGKVYVTAESRF
Y246 GLVTTLHYPAPKCNK
Y257 KCNKPTVYGVSPIHD
S260 KPTVYGVSPIHDKWE
Y288 GGQYGEVYVGVWKKY
Y295 YVGVWKKYSLTVAVK
K305 TVAVKTLKEDTMEVE
K316 MEVEEFLKEAAVMKE
T423 SRLMTGDTYTAHAGA
Y424 RLMTGDTYTAHAGAK
T425 LMTGDTYTAHAGAKF
T437 AKFPIKWTAPESLAY
Y444 TAPESLAYNTFSIKS
Y500 EGCPPKVYELMRACW
Y553 SSSSVVPYLPRLPIL
R556 SVVPYLPRLPILPSK
S562 PRLPILPSKTRTLKK
T566 ILPSKTRTLKKQVEN
S587 AQDATENSASSLAPG
S602 FIRGAQASSGSPALP
S603 IRGAQASSGSPALPR
S605 GAQASSGSPALPRKQ
S616 PRKQRDKSPSSLLED
S618 KQRDKSPSSLLEDAK
S619 QRDKSPSSLLEDAKE
S640 RKGGFFSSFMKKRNA
K644 FFSSFMKKRNAPTPP
T649 MKKRNAPTPPKRSSS
K652 RNAPTPPKRSSSFRE
S656 TPPKRSSSFREMENQ
Y668‑p ENQPHKKyELTGLPE
- gap
- gap
- gap
- gap
- gap
- gap
T697 SKLQLERTVSTSSQP
S699 LQLERTVSTSSQPEE
T700 QLERTVSTSSQPEEN
S701 LERTVSTSSQPEENV
S702 ERTVSTSSQPEENVD
T746 ATALPLRTPSGDLAI
S748 ALPLRTPSGDLAITE
S797 GEQPGWPSPAKAAPV
T808 AAPVLPTTHNHKVPV
S818 HKVPVLISPTLKHTP
T820 VPVLISPTLKHTPAD
S851 SEHQVTSSGDKDRPR
K863 RPRRVKPKCAPPPPP
S933 PQVPLPTSSISPAKM
S936 PLPTSSISPAKMANG
S989 LTEPVPNSQLVDTGH
T994 PNSQLVDTGHQLLDY
  mouse

 
S31 GSSAARPSGRRRDPA
T68 DGFEGDKTGGssPEV
S71‑p EGDKTGGssPEVLHR
S72‑p GDKTGGssPEVLHRP
F80 PEVLHRPFGCDAEsQ
S86‑p PFGCDAEsQALNEAI
S96 LNEAIRWSSKENLLG
S97 NEAIRWSSKENLLGA
Y116 PNLFVALYDFVASGD
S121 ALYDFVASGDNTLSI
Y139 EKLRVLGYNQNGEWS
Y161‑p QGWVPSNyITPVNSL
Y174‑p SLEKHSWyHGPVSRS
S194 LSSLINGSFLVRESE
S203 LVRESESSPGQLSIS
S208 ESSPGQLSISLRYEG
Y213 QLSISLRYEGRVyHY
Y218‑p LRYEGRVyHYRINTT
Y231‑p TTTDSKVyVTAESRF
Y261 GLVTTLHYPAPKCNK
Y272‑p KCNKPTVyGVSPIHD
S275 KPTVyGVSPIHDKWE
Y303 GGQYGEVYVGVWKKY
Y310 YVGVWKKYSLTVAVK
K320 TVAVKTFKEDTMEVE
K331 MEVEEFLKEAAVMKE
T438 SRLMTGDTytAHAGA
Y439‑p RLMTGDTytAHAGAK
T440‑p LMTGDTytAHAGAKF
T452 AKFPIKWTAPESLAY
Y459 TAPESLAYNTFSIKS
Y515 EGCPPKVYELMRACW
Y568‑p SSSSVVPyLPrLPLL
R571‑m2 SVVPyLPrLPLLPSK
S577 PrLPLLPSKTRTLRK
T581 LLPSKTRTLRKQGEN
L602 GLDAAESLASSSAPA
S618 FIRSTQASsGsPALP
S619‑p IRSTQASsGsPALPR
S621‑p STQASsGsPALPRKQ
S632‑p PRKQRDKsPssLLED
S634‑p KQRDKsPssLLEDAK
S635‑p QRDKsPssLLEDAKE
S656‑p RKGGFFSsFMKKRNA
K660 FFSsFMKKRNAPTPP
T665 MKKRNAPTPPKRSSs
K668 RNAPTPPKRSSsFRE
S672‑p TPPKRSSsFREMENQ
Y684‑p ENQPHKKyELTGNFS
Y719‑p NLVPAKCyGGSFAQR
T755‑p SGITGFFtPRLIKKT
S783 TSKPFPRSNstsSMS
S785‑p KPFPRSNstsSMSSG
T786‑p PFPRSNstsSMSSGL
S787‑p FPRSNstsSMSSGLP
T817 SKLQLERTVstSsQP
S819‑p LQLERTVstSsQPEE
T820‑p QLERTVstSsQPEEN
S821 LERTVstSsQPEENV
S822‑p ERTVstSsQPEENVD
A866 ATALPLRAPDPAITE
- gap
S915 GEQLGWSSPAKAVAV
T926‑gl AVAVLPTtHNHKVPV
S936‑p HKVPVLIsPtLKHTP
T938‑p VPVLIsPtLKHTPAD
S969 SEHQVTSSGDKDRPR
K981 RPRRVKPKCAPPPPP
S1051 PQVPLPTSSISPAKM
S1054 PLPTSSISPAKMANG
S1107 ITEPVPNSQLVDTGH
T1112 PNSQLVDTGHQLLDY
  rat

 
S31 GSSAARPSGRRRDPV
- gap
- gap
- gap
F78 AEVLHRPFGCDAESQ
S84 PFGCDAESQALNEAI
S94 LNEAIRWSSKENLLG
S95 NEAIRWSSKENLLGA
Y114 PNLFVALYDFVASGD
S119 ALYDFVASGDNTLSI
Y137 EKLRVLGYNQNGEWS
Y159 QGWVPSNYITPVNSL
Y172 SLEKHSWYHGPVSRS
S192 LSSLINGSFLVRESE
S201 LVRESESSPGQLSIS
S206 ESSPGQLSISLRYEG
Y211 QLSISLRYEGRVYHY
Y216 LRYEGRVYHYRINTT
Y229 TTTDSKVYVTAESRF
Y259 GLVTTLHYPAPKCNK
Y270 KCNKPTVYGVSPIHD
S273 KPTVYGVSPIHDKWE
Y301 GGQYGEVYVGVWKKY
Y308 YVGVWKKYSLTVAVK
K318 TVAVKTLKEDTMEVE
K329 MEVEEFLKEAAVMKE
T436‑p SRLMTGDtytAHAGA
Y437‑p RLMTGDtytAHAGAK
T438‑p LMTGDtytAHAGAKF
T450 AKFPIKWTAPESLAY
Y457 TAPESLAYNTFSIKS
Y513 EGCPPKVYELMRACW
Y566 SSSSVVPYLPRLPLL
R569 SVVPYLPRLPLLPSK
S575 PRLPLLPSKTRTLKK
T579 LLPSKTRTLKKQGEN
L600 GLDASEILASSSAPG
S615 FIRSTQASSGSPALP
S616 IRSTQASSGSPALPR
S618 STQASSGSPALPRKQ
S629‑p PRKQRDKsPSSLLED
S631 KQRDKsPSSLLEDAK
S632 QRDKsPSSLLEDAKE
S653 RKGGFFSSFMKKRNA
K657 FFSSFMKKRNAPMPP
M662 MKKRNAPMPPKRSSS
K665 RNAPMPPKRSSSFRE
S669 MPPKRSSSFREMENQ
Y681 ENQPHKKYELTGNFS
Y716 NLVPAKCYGGSFAQR
T735 DDDSGFFTPRLIKKT
S763 TSKPFPRSNSTSSMS
S765 KPFPRSNSTSSMSSG
T766 PFPRSNSTSSMSSGL
S767 FPRSNSTSSMSSGLP
T797‑p SKLQLERtVsTSsQP
S799‑p LQLERtVsTSsQPEE
T800 QLERtVsTSsQPEEN
S801 LERtVsTSsQPEENV
S802‑p ERtVsTSsQPEENVD
A846 ATALALRAPDPAITE
- gap
S895 AEQPGWSSPAKAVAV
T906 AVAVLPTTHNHKVPV
S916‑p HKVPVLIsPTLKHTA
T918 VPVLIsPTLKHTAAD
S949 SEHQVTSSGDKDRPR
K961 RPRRVKPKCAPPPPP
S1031 PQVPLPTSSISPAKM
S1034 PLPTSSISPAKMANG
S1087 ITEPVPHSQLVDTGH
T1092 PHSQLVDTGHQLLHY
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