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Protein Page:
ACTC1 (human)

Overview
ACTC1 Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Belongs to the actin family. Note: This description may include information from UniProtKB.
Protein type: Cell development/differentiation; Contractile; Cytoskeletal; Motility/polarity/chemotaxis; Myosin-binding
Chromosomal Location of Human Ortholog: 15q14
Cellular Component: actin filament; cytoplasm; cytosol; extracellular space; filopodium; focal adhesion; I band; lamellipodium; membrane; sarcomere
Molecular Function: ATP binding; ATPase activity; myosin binding
Biological Process: actin filament-based movement; actin-myosin filament sliding; actomyosin structure organization and biogenesis; apoptosis; cardiac muscle morphogensis; cardiac myofibril assembly; heart contraction; muscle filament sliding; muscle thin filament assembly
Disease: Atrial Septal Defect 5; Cardiomyopathy, Dilated, 1r; Cardiomyopathy, Familial Hypertrophic, 11
Reference #:  P68032 (UniProtKB)
Alt. Names/Synonyms: ACTC; ACTC1; Actin, alpha cardiac muscle 1; actin, alpha, cardiac muscle 1; Alpha-cardiac actin; ASD5; CMD1R; CMH11
Gene Symbols: ACTC1
Molecular weight: 42,019 Da
Basal Isoelectric point: 5.23  Predict pI for various phosphorylation states
CST Pathways:  Death Receptor Signaling
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

ACTC1

Protein Structure Not Found.


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