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Protein Page:
Akt1 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitylation
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
Akt1 an oncogenic AGC kinase that plays a critical role in regulating cell survival and metabolism in many different signaling pathways. Dual phosphorylation is required for its activation. T308 is phosphorylated by PDK1 in the PI3 kinase pathway, and S473 is phosphorylated by mTOR in the mTORC2 pathway. The 'Lys-63'-linked ubiquitination of AKT1 by TRAF6 is important for its translocation to the plasma membrane, phosphorylation, and activation. When Akt is fully phosphorylated it translocates into the nucleus, undergoes 'Lys-48'-polyubiquitination catalyzed by TTC3, leading to its proteosomal degradation. Hyperactive or overexpressed in a number of cancers including breast, prostate, lung, pancreatic, liver, ovarian and colorectal. Over 160 protein substrates are known including many that regulate transcription, metabolism, apoptosis, cell cycle, and growth. Note: This description may include information from UniProtKB.
Protein type: Oncoprotein; Kinase, protein; Protein kinase, AGC; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); AGC group; AKT family
Chromosomal Location of Human Ortholog: 14q32.32
Cellular Component: cytoplasm; cytosol; microtubule cytoskeleton; nucleoplasm; nucleus; plasma membrane; vesicle
Molecular Function: ATP binding; enzyme binding; identical protein binding; kinase activity; nitric-oxide synthase regulator activity; phosphatidylinositol-3,4,5-triphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity
Biological Process: activated T cell apoptosis; cell differentiation; cell proliferation; cellular response to insulin stimulus; endocrine pancreas development; G-protein coupled receptor protein signaling pathway; G1/S-specific positive regulation of cyclin-dependent protein kinase activity; insulin receptor signaling pathway; insulin-like growth factor receptor signaling pathway; negative regulation of apoptosis; negative regulation of autophagy; negative regulation of caspase activity; negative regulation of fatty acid beta-oxidation; negative regulation of protein kinase activity; negative regulation of proteolysis; nitric oxide biosynthetic process; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; phosphoinositide-mediated signaling; phosphorylation; platelet activation; positive regulation of blood vessel endothelial cell migration; positive regulation of cell growth; positive regulation of cellular protein metabolic process; positive regulation of endodeoxyribonuclease activity; positive regulation of endothelial cell proliferation; positive regulation of epidermal growth factor receptor signaling pathway; positive regulation of fat cell differentiation; positive regulation of glucose import; positive regulation of glycogen biosynthetic process; positive regulation of lipid biosynthetic process; positive regulation of nitric oxide biosynthetic process; positive regulation of nitric-oxide synthase activity; positive regulation of peptidyl-serine phosphorylation; positive regulation of protein amino acid phosphorylation; positive regulation of transcription factor activity; protein amino acid autophosphorylation; protein amino acid phosphorylation; protein import into nucleus, translocation; protein modification process; regulation of cell migration; regulation of glycogen biosynthetic process; regulation of mRNA stability; regulation of nitric-oxide synthase activity; regulation of phosphoinositide 3-kinase cascade; response to heat; response to oxidative stress; signal transduction; T cell costimulation
Disease: Breast Cancer; Colorectal Cancer; Cowden Syndrome 6; Ovarian Cancer; Proteus Syndrome; Schizophrenia
Reference #:  P31749 (UniProtKB)
Alt. Names/Synonyms: AKT; AKT1; AKT1 kinase; MGC99656; PKB; PKB-ALPHA; PRKBA; Protein kinase B; Proto-oncogene c-Akt; RAC; rac protein kinase alpha; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RAC-PK-alpha; v-akt murine thymoma viral oncogene homolog 1
Gene Symbols: AKT1
Molecular weight: 55,686 Da
Basal Isoelectric point: 5.75  Predict pI for various phosphorylation states
CST Pathways:  Adherens Junction Dynamics  |  Alzheimer's Disease  |  AMPK Signaling  |  Angiogenesis  |  Apoptosis Regulation  |  B Cell Receptor Signaling  |  ErbB/HER Signaling  |  ESC Pluripotency and Differentiation  |  G1/S Checkpoint  |  IL6 Signaling  |  Inhibition of Apoptosis  |  Microtubule Dynamics  |  Mitochondrial Control of Apoptosis  |  mTOR Signaling  |  NF-kB Signaling  |  PI3K/Akt Signaling  |  Protein Kinase C Signaling  |  T Cell Receptor Signaling  |  TGF-ß Signaling  |  Translation: eIF4E and p70S6K  |  Warburg Effect
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Akt1

Protein Structure Not Found.
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Substrate Sequence Logo
Sequence Logo

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Sites Implicated In
apoptosis, altered: T308‑p, S473‑p
apoptosis, induced: T450‑p
apoptosis, inhibited: T72‑p, S129‑p, S246‑p, T308‑p, S473‑p
carcinogenesis, altered: S473‑p
carcinogenesis, induced: T308‑p, S473‑p
cell cycle regulation: Y176‑p, T308‑p, S473‑p
cell differentiation, altered: T450‑p, S473‑p
cell growth, altered: T308‑p, S473‑p
cell growth, induced: T308‑p, S473‑p
cell motility, altered: T308‑p, S473‑p
cell motility, induced: S473‑p
cytoskeletal reorganization: T308‑p, S473‑p
transcription, altered: Y176‑p, T308‑p, Y315‑p, T450‑p, S473‑p
transcription, induced: S129‑p
translation, altered: T450‑p
activity, induced: T308‑p, T450‑p, S473‑p
enzymatic activity, induced: K8‑ub, K14‑ub, T72‑p, S124‑p, S129‑p, Y176‑p, S246‑p, T308‑p, Y315‑p, Y326‑p, T450‑p, S473‑p, Y474‑p
enzymatic activity, inhibited: T305‑gl, T312‑gl, T450‑p
intracellular localization: K8‑ub, K14‑ub, Y176‑p, T308‑p, S473‑p
molecular association, regulation: T92‑p, T308‑p, T450‑p, S473‑p
phosphorylation: K8‑ub, K14‑ub, T92‑p, T305‑gl, T308‑p, T312‑gl, T450‑p, S473‑p
protein conformation: T308‑p, T450‑p
protein degradation: S473‑p
protein stabilization: T92‑p, T450‑p
ubiquitination: T450‑p

Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment



 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

► Hide Isoforms
 
1 2 K8‑ub MSDVAIVkEGWLHkR
1 0 K14‑ub VkEGWLHkRGEYIKT
0 2 K30‑ub RPRYFLLkNDGTFIG
1 0 T34 FLLkNDGTFIGYKER
0 1 T65‑p AQCQLMKtERPRPNt
2 0 T72‑p tERPRPNtFIIRCLQ
0 1 T87‑p WTTVIERtFHVEtPE
1 1 T92‑p ERtFHVEtPEEREEW
0 1 E117 LKKQEEEEMDFRsGs
0 9 S122‑p EEEMDFRsGsPsDNs
5 19 S124‑p EMDFRsGsPsDNsGA
0 21 S126‑p DFRsGsPsDNsGAEE
0 1 S126‑gl DFRsGsPsDNsGAEE
9 36 S129‑p sGsPsDNsGAEEMEV
0 1 S129‑gl sGsPsDNsGAEEMEV
0 2 S137‑p GAEEMEVsLAKPKHR
0 8 T146‑p AKPKHRVtMNEFEYL
2 1 Y176‑p EKATGRYyAMKILKK
1 0 T211‑p NSRHPFLtALKYSFQ
1 0 S246‑p LSRERVFsEDRARFY
0 2 K276‑ub NVVYRDLkLENLMLD
3 1 K276‑sm NVVYRDLkLENLMLD
1 0 T291‑p KDGHIKItDFGLCKE
1 0 K301‑sm GLCKEGIkDGAtMKt
0 7 T305‑p EGIkDGAtMKtFCGt
1 1 T305‑gl EGIkDGAtMKtFCGt
542 22 T308‑p kDGAtMKtFCGtPEy
1 0 T308‑gl kDGAtMKtFCGtPEy
1 5 T312‑p tMKtFCGtPEyLAPE
1 1 T312‑gl tMKtFCGtPEyLAPE
5 14 Y315‑p tFCGtPEyLAPEVLE
3 27 Y326‑p EVLEDNDyGRAVDWW
0 2 K377‑ub RTLGPEAksLLSGLL
0 1 S378‑p TLGPEAksLLSGLLK
0 1 S396‑p KQRLGGGsEDAKEIM
0 2 Y417‑p GIVWQHVyEKkLSPP
0 1 K420‑ac WQHVyEKkLSPPFkP
0 1 K426‑ac KkLSPPFkPQVTSET
0 2 Y437‑p TSETDTRyFDEEFtA
0 1 T443‑p RyFDEEFtAQMItIt
0 1 T448‑p EFtAQMItItPPDQD
23 4 T450‑p tAQMItItPPDQDDs
0 1 S457‑p tPPDQDDsMECVDSE
1342 61 S473‑p RPHFPQFsysAsGtA
5 0 S473‑gl RPHFPQFsysAsGtA
1 14 Y474‑p PHFPQFsysAsGtA_
0 3 S475‑p HFPQFsysAsGtA__
1 4 S477‑p PQFsysAsGtA____
1 15 T479‑p FsysAsGtA______
13461 : Phospho-Akt1 (Ser129) (D4P7F) Rabbit mAb
2918 : Phospho-Akt (Thr308) (C31E5E) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
2965 : Phospho-Akt (Thr308) (C31E5E) Rabbit mAb
3375 : Phospho-Akt (Thr308) (C31E5E) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
4056 : Phospho-Akt (Thr308) (244F9) Rabbit mAb
5056 : Phospho-Akt (Thr308) (C31E5E) Rabbit mAb (Biotinylated)
5106 : Phospho-Akt (Thr308) (L32A4) Mouse mAb
9088 : Phospho-Akt (Thr308) (C31E5E) Rabbit mAb (PE Conjugate)
9275 : Phospho-Akt (Thr308) Antibody
13038 : Phospho-Akt (Thr308) (D25E6) XP(R) Rabbit mAb
13842 : Phospho-Akt (Thr308) (D25E6) XP(R) Rabbit mAb (PE Conjugate)
9267 : Phospho-Akt (Thr450) Antibody
12178 : Phospho-Akt (Thr450) (D5G4) Rabbit mAb
2336 : Phospho-Akt (Ser473) (193H12) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
2337 : Phospho-Akt (Ser473) (193H12) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
3787 : Phospho-Akt (Ser473) (736E11) Rabbit mAb
4051 : Phospho-Akt (Ser473) (587F11) Mouse mAb
4058 : Phospho-Akt (Ser473) (193H12) Rabbit mAb
4060 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb
4070 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (Sepharose Bead Conjugate)
4071 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
4075 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
5012 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (Biotinylated)
5102 : Phospho-Akt (Ser473) (587F11) Mouse mAb (Biotinylated)
5315 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (PE Conjugate)
9018 : Phospho-Akt1 (Ser473) (D7F10) XP(R) Rabbit mAb (Akt1 Specific)
9271 : Phospho-Akt (Ser473) Antibody
9563 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (Magnetic Bead Conjugate)
11962 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (APC Conjugate)
12694 : Phospho-Akt (Ser473) (D9W9U) Mouse mAb
15116 : Phospho-Akt (Ser473) (D9W9U) Mouse mAb (Biotinylated)
  Akt1 iso2  
- gap
- gap
- gap
- gap
T3 _____MKTERPRPNT
T10 TERPRPNTFIIRCLQ
T25 WTTVIERTFHVETPE
T30 ERTFHVETPEEREEW
E55 LKKQEEEEMDFRSGS
S60 EEEMDFRSGSPSDNS
S62 EMDFRSGSPSDNSGA
S64 DFRSGSPSDNSGAEE
S64 DFRSGSPSDNSGAEE
S67 SGSPSDNSGAEEMEV
S67 SGSPSDNSGAEEMEV
S75 GAEEMEVSLAKPKHR
T84 AKPKHRVTMNEFEYL
Y114 EKATGRYYAMKILKK
T149 NSRHPFLTALKYSFQ
S184 LSRERVFSEDRARFY
K214 NVVYRDLKLENLMLD
K214 NVVYRDLKLENLMLD
T229 KDGHIKITDFGLCKE
K239 GLCKEGIKDGATMKT
T243 EGIKDGATMKTFCGT
T243 EGIKDGATMKTFCGT
T246 KDGATMKTFCGTPEY
T246 KDGATMKTFCGTPEY
T250 TMKTFCGTPEYLAPE
T250 TMKTFCGTPEYLAPE
Y253 TFCGTPEYLAPEVLE
Y264 EVLEDNDYGRAVDWW
K315 RTLGPEAKSLLSGLL
S316 TLGPEAKSLLSGLLK
S334 KQRLGGGSEDAKEIM
Y355 GIVWQHVYEKKLSPP
K358 WQHVYEKKLSPPFKP
K364 KKLSPPFKPQVTSET
Y375 TSETDTRYFDEEFTA
T381 RYFDEEFTAQMITIT
T386 EFTAQMITITPPDQD
T388 TAQMITITPPDQDDS
S395 TPPDQDDSMECVDSE
S411 RPHFPQFSYSASGTA
S411 RPHFPQFSYSASGTA
Y412 PHFPQFSYSASGTA_
S413 HFPQFSYSASGTA__
S415 PQFSYSASGTA____
T417 FSYSASGTA______
  mouse

 
K8 MNDVAIVKEGWLHKR
K14 VKEGWLHKRGEYIKT
K30‑ub RPRYFLLkNDGTFIG
T34 FLLkNDGTFIGYKER
T65 AQCQLMKTERPRPNT
T72 TERPRPNTFIIRCLQ
T87 WTTVIERTFHVETPE
T92 ERTFHVETPEEREEW
T117‑p LKRQEEEtMDFRsGs
S122‑p EEtMDFRsGsPsDNs
S124‑p tMDFRsGsPsDNsGA
S126‑p DFRsGsPsDNsGAEE
S126 DFRsGsPSDNsGAEE
S129‑p sGsPsDNsGAEEMEV
S129 sGsPsDNSGAEEMEV
S137‑p GAEEMEVsLAKPKHR
T146 AKPKHRVTMNEFEYL
Y176‑p EKATGRYyAMKILKK
T211 NSRHPFLTALKYSFQ
S246 LSRERVFSEDRARFY
K276‑ub NVVYRDLkLENLMLD
K276 NVVYRDLKLENLMLD
T291 KDGHIKITDFGLCKE
K301 GLCKEGIKDGAtMKt
T305‑p EGIKDGAtMKtFCGt
T305 EGIKDGATMKtFCGt
T308‑p KDGAtMKtFCGtPEy
T308 KDGAtMKTFCGtPEy
T312‑p tMKtFCGtPEyLAPE
T312 tMKtFCGTPEyLAPE
Y315‑p tFCGtPEyLAPEVLE
Y326‑p EVLEDNDyGRAVDWW
K377 RTLGPEAKSLLSGLL
S378 TLGPEAKSLLSGLLK
S396 TQRLGGGSEDAKEIM
Y417 NIVWQDVYEKKLSPP
K420 WQDVYEKKLSPPFKP
K426 KKLSPPFKPQVTSET
Y437 TSETDTRYFDEEFTA
T443 RYFDEEFTAQMITIt
T448 EFTAQMITItPPDQD
T450‑p TAQMITItPPDQDDS
S457 tPPDQDDSMECVDSE
S473‑p RPHFPQFsysAsGtA
S473‑gl RPHFPQFsysAsGtA
Y474‑p PHFPQFsysAsGtA_
S475‑p HFPQFsysAsGtA__
S477‑p PQFsysAsGtA____
T479‑p FsysAsGtA______
2918 : Phospho-Akt (Thr308) (C31E5E) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
2965 : Phospho-Akt (Thr308) (C31E5E) Rabbit mAb
3375 : Phospho-Akt (Thr308) (C31E5E) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
4056 : Phospho-Akt (Thr308) (244F9) Rabbit mAb
5056 : Phospho-Akt (Thr308) (C31E5E) Rabbit mAb (Biotinylated)
5106 : Phospho-Akt (Thr308) (L32A4) Mouse mAb
9088 : Phospho-Akt (Thr308) (C31E5E) Rabbit mAb (PE Conjugate)
9275 : Phospho-Akt (Thr308) Antibody
13038 : Phospho-Akt (Thr308) (D25E6) XP(R) Rabbit mAb
13842 : Phospho-Akt (Thr308) (D25E6) XP(R) Rabbit mAb (PE Conjugate)
9267 : Phospho-Akt (Thr450) Antibody
12178 : Phospho-Akt (Thr450) (D5G4) Rabbit mAb
2336 : Phospho-Akt (Ser473) (193H12) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
2337 : Phospho-Akt (Ser473) (193H12) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
3787 : Phospho-Akt (Ser473) (736E11) Rabbit mAb
4051 : Phospho-Akt (Ser473) (587F11) Mouse mAb
4058 : Phospho-Akt (Ser473) (193H12) Rabbit mAb
4060 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb
4070 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (Sepharose Bead Conjugate)
4071 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
4075 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
5012 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (Biotinylated)
5102 : Phospho-Akt (Ser473) (587F11) Mouse mAb (Biotinylated)
5315 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (PE Conjugate)
9018 : Phospho-Akt1 (Ser473) (D7F10) XP(R) Rabbit mAb (Akt1 Specific)
9271 : Phospho-Akt (Ser473) Antibody
9563 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (Magnetic Bead Conjugate)
11962 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (APC Conjugate)
12694 : Phospho-Akt (Ser473) (D9W9U) Mouse mAb
15116 : Phospho-Akt (Ser473) (D9W9U) Mouse mAb (Biotinylated)
  rat

 
K8 MNDVAIVKEGWLHKR
K14 VKEGWLHKRGEYIKT
K30 RPRYFLLKNDGtFIG
T34‑p FLLKNDGtFIGYKER
T65 AQCQLMKTERPRPNT
T72 TERPRPNTFIIRCLQ
T87 WTTVIERTFHVETPE
T92 ERTFHVETPEEREEW
T117 LKRQEEETMDFRSGs
S122 EETMDFRSGsPSDNs
S124‑p TMDFRSGsPSDNsGA
S126 DFRSGsPSDNsGAEE
S126 DFRSGsPSDNsGAEE
S129‑p SGsPSDNsGAEEMEV
S129 SGsPSDNSGAEEMEV
A137 GAEEMEVALAKPKHR
T146 AKPKHRVTMNEFEYL
Y176 EKATGRYYAMKILKK
T211 NSRHPFLTALKYSFQ
S246 LSRERVFSEDRARFY
K276 NVVYRDLKLENLMLD
K276 NVVYRDLKLENLMLD
T291 KDGHIKITDFGLCKE
K301 GLCKEGIKDGATMKt
T305 EGIKDGATMKtFCGT
T305 EGIKDGATMKtFCGT
T308‑p KDGATMKtFCGTPEy
T308 KDGATMKTFCGTPEy
T312 TMKtFCGTPEyLAPE
T312 TMKtFCGTPEyLAPE
Y315‑p tFCGTPEyLAPEVLE
Y326 EVLEDNDYGRAVDWW
K377 RTLGPEAKSLLSGLL
S378 TLGPEAKSLLSGLLK
S396 TQRLGGGSEDAKEIM
Y417 NIVWQDVYEKKLSPP
K420 WQDVYEKKLSPPFKP
K426 KKLSPPFKPQVTSET
Y437 TSETDTRYFDEEFTA
T443 RYFDEEFTAQMITIt
T448 EFTAQMITItPPDQD
T450‑p TAQMITItPPDQDDS
S457 tPPDQDDSMECVDSE
S473‑p RPHFPQFsYSASGTA
S473‑gl RPHFPQFsYSASGTA
Y474 PHFPQFsYSASGTA_
S475 HFPQFsYSASGTA__
S477 PQFsYSASGTA____
T479 FsYSASGTA______
2918 : Phospho-Akt (Thr308) (C31E5E) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
2965 : Phospho-Akt (Thr308) (C31E5E) Rabbit mAb
3375 : Phospho-Akt (Thr308) (C31E5E) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
4056 : Phospho-Akt (Thr308) (244F9) Rabbit mAb
5056 : Phospho-Akt (Thr308) (C31E5E) Rabbit mAb (Biotinylated)
5106 : Phospho-Akt (Thr308) (L32A4) Mouse mAb
9088 : Phospho-Akt (Thr308) (C31E5E) Rabbit mAb (PE Conjugate)
9275 : Phospho-Akt (Thr308) Antibody
13038 : Phospho-Akt (Thr308) (D25E6) XP(R) Rabbit mAb
13842 : Phospho-Akt (Thr308) (D25E6) XP(R) Rabbit mAb (PE Conjugate)
9267 : Phospho-Akt (Thr450) Antibody
12178 : Phospho-Akt (Thr450) (D5G4) Rabbit mAb
2336 : Phospho-Akt (Ser473) (193H12) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
2337 : Phospho-Akt (Ser473) (193H12) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
3787 : Phospho-Akt (Ser473) (736E11) Rabbit mAb
4051 : Phospho-Akt (Ser473) (587F11) Mouse mAb
4058 : Phospho-Akt (Ser473) (193H12) Rabbit mAb
4060 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb
4070 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (Sepharose Bead Conjugate)
4071 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
4075 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
5012 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (Biotinylated)
5102 : Phospho-Akt (Ser473) (587F11) Mouse mAb (Biotinylated)
5315 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (PE Conjugate)
9018 : Phospho-Akt1 (Ser473) (D7F10) XP(R) Rabbit mAb (Akt1 Specific)
9271 : Phospho-Akt (Ser473) Antibody
9563 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (Magnetic Bead Conjugate)
11962 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (APC Conjugate)
12694 : Phospho-Akt (Ser473) (D9W9U) Mouse mAb
15116 : Phospho-Akt (Ser473) (D9W9U) Mouse mAb (Biotinylated)
  fruit fly

 
K109 TEQTQVVKEGWLMKR
K115 VKEGWLMKRGEHIKN
H131 RQRYFVLHSDGRLMG
R135 FVLHSDGRLMGYRSK
T167 VRGCQIMTVDRPKPF
T175 VDRPKPFTFIIRGLQ
T190 WTTVIERTFAVESEL
S195 ERTFAVESELERQQW
M229 TPSEQTDMTDVDMAT
M234 TDMTDVDMATIAEDE
T236 MTDVDMATIAEDELS
A238 DVDMATIAEDELSEQ
A238 DVDMATIAEDELSEQ
E241 MATIAEDELSEQFSV
E241 MATIAEDELSEQFSV
C253 FSVQGTTCNSSGVKK
T262 SSGVKKVTLENFEFL
Y292 EKATAKLYAIKILKK
I327 STNHPFLISLKYSFQ
T362 LSHERIFTEDRTRFY
K391 GIIYRDLKLENLLLD
K391 GIIYRDLKLENLLLD
A406 KDGHIKVADFGLCKE
T416 GLCKEDITYGRTTKT
T420 EDITYGRTTKTFCGT
T420 EDITYGRTTKTFCGT
T423 TYGRTTKTFCGTPEY
T423 TYGRTTKTFCGTPEY
T427 TTKTFCGTPEYLAPE
T427 TTKTFCGTPEYLAPE
Y430 TFCGTPEYLAPEVLD
Y441 EVLDDNDYGQAVDWW
K492 RNITDEAKNLLAGLL
N493 NITDEAKNLLAGLLA
K511 KKRLGGGKDDVKEIQ
V532 SINWTDLVLKKIPPP
K535 WTDLVLKKIPPPFKP
K541 KKIPPPFKPQVTSDT
Y552 TSDTDTRYFDKEFTG
T558 RYFDKEFTGESVELT
E563 EFTGESVELTPPDPT
T565 TGESVELTPPDPTGP
P572 TPPDPTGPLGSIAEE
S586 EPLFPQFSYQGDMAS
S586 EPLFPQFSYQGDMAS
Y587 PLFPQFSYQGDMAST
Q588 LFPQFSYQGDMASTL
T603 GTSSHISTSTSLASM
T605 SSHISTSTSLASMQ_
4054 : Phospho-Drosophila Akt (Ser505) Antibody
4060 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb
5012 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (Biotinylated)
5315 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (PE Conjugate)
9271 : Phospho-Akt (Ser473) Antibody
11962 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (APC Conjugate)
  cow

 
K8 MNDVAIVKEGWLHKR
K14 VKEGWLHKRGEYIKT
K30 RPRYFLLKNDGTFIG
T34 FLLKNDGTFIGYKER
T65 AQCQLMKTERPRPNT
T72 TERPRPNTFIIRCLQ
T87 WTTVIERTFHVETPE
T92 ERTFHVETPEEREEW
T117 LKRQEEETMDFRSGS
S122 EETMDFRSGSPGENS
S124 TMDFRSGSPGENSGA
G126 DFRSGSPGENSGAEE
G126 DFRSGSPGENSGAEE
S129 SGSPGENSGAEEMEV
S129 SGSPGENSGAEEMEV
S137 GAEEMEVSLAKPKHR
T146 AKPKHRVTMNDFEYL
Y176 EKATGRYYAMKILKK
T211 NSRHPFLTALKYSFQ
S246 LSRERVFSEDRARFY
K276 EVVYRDLKLENLMLD
K276 EVVYRDLKLENLMLD
T291 KDGHIKITDFGLCKE
K301 GLCKEGIKDGATMKt
T305 EGIKDGATMKtFCGT
T305 EGIKDGATMKtFCGT
T308‑p KDGATMKtFCGTPEY
T308 KDGATMKTFCGTPEY
T312 TMKtFCGTPEYLAPE
T312 TMKtFCGTPEYLAPE
Y315 tFCGTPEYLAPEVLE
Y326 EVLEDNDYGRAVDWW
K377 RTLSPEAKSLLSGLL
S378 TLSPEAKSLLSGLLK
S396 KQRLGGGSEDAKEIM
Y417 SIVWQDVYEKKLSPP
K420 WQDVYEKKLSPPFKP
K426 KKLSPPFKPQVTSET
Y437 TSETDTRYFDEEFTA
T443 RYFDEEFTAQMITIT
T448 EFTAQMITITPPDQD
T450 TAQMITITPPDQDDS
S457 TPPDQDDSMEGVDSE
S473‑p RPHFPQFsYSASATA
S473 RPHFPQFSYSASATA
Y474 PHFPQFsYSASATA_
S475 HFPQFsYSASATA__
S477 PQFsYSASATA____
T479 FsYSASATA______
2918 : Phospho-Akt (Thr308) (C31E5E) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
2965 : Phospho-Akt (Thr308) (C31E5E) Rabbit mAb
3375 : Phospho-Akt (Thr308) (C31E5E) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
4056 : Phospho-Akt (Thr308) (244F9) Rabbit mAb
5056 : Phospho-Akt (Thr308) (C31E5E) Rabbit mAb (Biotinylated)
5106 : Phospho-Akt (Thr308) (L32A4) Mouse mAb
9088 : Phospho-Akt (Thr308) (C31E5E) Rabbit mAb (PE Conjugate)
9275 : Phospho-Akt (Thr308) Antibody
2336 : Phospho-Akt (Ser473) (193H12) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
2337 : Phospho-Akt (Ser473) (193H12) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
3787 : Phospho-Akt (Ser473) (736E11) Rabbit mAb
4051 : Phospho-Akt (Ser473) (587F11) Mouse mAb
4058 : Phospho-Akt (Ser473) (193H12) Rabbit mAb
4060 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb
4070 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (Sepharose Bead Conjugate)
4071 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
4075 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
5012 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (Biotinylated)
5102 : Phospho-Akt (Ser473) (587F11) Mouse mAb (Biotinylated)
5315 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (PE Conjugate)
9271 : Phospho-Akt (Ser473) Antibody
9563 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (Magnetic Bead Conjugate)
11962 : Phospho-Akt (Ser473) (D9E) XP(R) Rabbit mAb (APC Conjugate)
12694 : Phospho-Akt (Ser473) (D9W9U) Mouse mAb
15116 : Phospho-Akt (Ser473) (D9W9U) Mouse mAb (Biotinylated)
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