May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; C2H2-type zinc finger protein
Molecular Function: DNA binding; metal ion binding; protein binding; transcription factor activity
Biological Process: cell differentiation; negative regulation of apoptosis; negative regulation of cell proliferation; negative regulation of transcription from RNA polymerase II promoter; positive regulation of apoptosis; positive regulation of cell differentiation; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of protein amino acid phosphorylation; positive regulation of protein catabolic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter, mitotic; regulation of mitotic cell cycle; regulation of protein heterodimerization activity; regulation of transcription, DNA-dependent; release of cytoplasmic sequestered NF-kappaB; transcription, DNA-dependent
LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.