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Protein Page:
Kv1.3 (human)

Overview
Kv1.3 Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.3/KCNA3 sub-subfamily. Note: This description may include information from UniProtKB.
Protein type: Channel, potassium; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 1p13.3
Cellular Component: plasma membrane
Molecular Function: delayed rectifier potassium channel activity; voltage-gated ion channel activity
Biological Process: potassium ion transport
Reference #:  P22001 (UniProtKB)
Alt. Names/Synonyms: HGK5; HLK3; HPCN3; HUKIII; KCNA3; KV1.3; MK3; PCN3; potassium channel 3; Potassium voltage-gated channel subfamily A member 3; potassium voltage-gated channel, shaker-related subfamily, member 3; type n potassium channel; Voltage-gated K(+) channel HuKIII; voltage-gated potassium channel protein Kv1.3; Voltage-gated potassium channel subunit Kv1.3
Gene Symbols: KCNA3
Molecular weight: 63,842 Da
Basal Isoelectric point: 5.61  Predict pI for various phosphorylation states
Select Structure to View Below

Kv1.3

Protein Structure Not Found.
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