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Protein Page:
FNDC5 (human)

FNDC5 Irisin: mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA. 4 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 1p35.1
Cellular Component: endoplasmic reticulum; extracellular region; plasma membrane
Biological Process: response to muscle activity
Reference #:  Q8NAU1 (UniProtKB)
Alt. Names/Synonyms: fibronectin type III domain containing 5; Fibronectin type III domain-containing protein 5; Fibronectin type III repeat-containing protein 2; FNDC5; FRCP2
Gene Symbols: FNDC5
Molecular weight: 23,659 Da
Basal Isoelectric point: 6.91  Predict pI for various phosphorylation states
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Protein Structure Not Found.
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