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Protein Page:
GPR18 (human)

GPR18 Receptor for N-arachidonyl glycine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. May contribute to regulation of the immune system. Belongs to the G-protein coupled receptor 1 family. Note: This description may include information from UniProtKB.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 13q32
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity
Biological Process: elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); positive regulation of Rho protein signal transduction; T cell differentiation
Reference #:  Q14330 (UniProtKB)
Alt. Names/Synonyms: G protein-coupled receptor 18; G-protein coupled receptor 18; GPCRW; GPR18; N-arachidonyl glycine receptor; NAGly receptor
Gene Symbols: GPR18
Molecular weight: 38,134 Da
Basal Isoelectric point: 9.38  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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