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Protein Page:
GBX2 (human)

Overview
GBX2 May act as a transcription factor for cell pluripotency and differentiation in the embryo. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 2q37.2
Cellular Component: nucleus
Molecular Function: transcription factor activity
Biological Process: autonomic nervous system development; axon guidance; cerebellum development; forebrain neuron development; granule cell precursor proliferation; inner ear morphogenesis; midbrain-hindbrain boundary morphogenesis; nervous system development; neural crest cell migration; patterning of blood vessels; positive regulation of transcription from RNA polymerase II promoter; rhombomere 2 development; thalamus development; transcription from RNA polymerase II promoter
Reference #:  P52951 (UniProtKB)
Alt. Names/Synonyms: Gastrulation and brain-specific homeobox protein 2; gastrulation brain homeo box 2; gastrulation brain homeobox 2; GBX2; Homeobox protein GBX-2
Gene Symbols: GBX2
Molecular weight: 37,348 Da
Basal Isoelectric point: 8.43  Predict pI for various phosphorylation states
Select Structure to View Below

GBX2

Protein Structure Not Found.


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Modification Sites and Domains  

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 S160‑p GFLAKEGsLLAFSAA
0 1 T242‑p SGAAGSTtSTGKNRR
0 2 S312‑p VKAGNANsKtGEPSR
0 2 T314‑p AGNANsKtGEPSRNP
  mouse

 
S160 AFLAKEGSLLAFSAA
T242 GGAAGSTTSTGKNRR
S312‑p VKAGNANsKtGEPSR
T314‑p AGNANsKtGEPSRNP
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