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Protein Page:
Oct9 (human)

Overview
Oct9 Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of neurons in the mature brain. Defects in POU3F4 are a cause of deafness X-linked type 2 (DFNX2). A mixed type of deafness characterized by both conductive hearing loss resulting from stapes (perilymphatic gusher) fixation and progressive sensorineural deafness. Belongs to the POU transcription factor family. Class- 3 subfamily. Note: This description may include information from UniProtKB.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: Xq21.1
Cellular Component: nucleus
Molecular Function: AT DNA binding; transcription factor activity
Biological Process: forebrain neuron differentiation; regulation of transcription from RNA polymerase II promoter; sensory perception of sound; transcription from RNA polymerase II promoter
Disease: Deafness, X-linked 2
Reference #:  P49335 (UniProtKB)
Gene Symbols: POU3F4
Molecular weight: 39,427 Da
Basal Isoelectric point: 7.07  Predict pI for various phosphorylation states
Select Structure to View Below

Oct9

Protein Structure Not Found.


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Modification Sites and Domains  

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 4 S265‑p EADSSTGsPtsIDKI
0 1 T267‑p DSSTGsPtsIDKIAA
0 1 S268‑p SSTGsPtsIDKIAAQ
  mouse

 
S265‑p EADSSTGsPTSIDKI
T267 DSSTGsPTSIDKIAA
S268 SSTGsPTSIDKIAAQ
  rat

 
S265‑p EADSSTGsPTSIDKI
T267 DSSTGsPTSIDKIAA
S268 SSTGsPTSIDKIAAQ
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