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Protein Page:
GSX1 (human)

Overview
GSX1 Probable transcription factor that binds to the DNA sequence 5'-GC[TA][AC]ATTA[GA]-3'. Activates the transcription of the GHRH gene. Plays an important role in pituitary development. Belongs to the Antp homeobox family. Note: This description may include information from UniProtKB.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 13q12.2
Cellular Component: nucleus
Molecular Function: sequence-specific DNA binding
Biological Process: adenohypophysis development; hypothalamus development; neuron fate commitment; positive regulation of transcription from RNA polymerase II promoter; spinal cord association neuron differentiation; transcription from RNA polymerase II promoter
Reference #:  Q9H4S2 (UniProtKB)
Alt. Names/Synonyms: genomic screened homeo box 1; GS homeo box protein 1; GS homeobox 1; Gsh-1; GSH1; GSX1; Homeobox protein GSH-1
Gene Symbols: GSX1
Molecular weight: 27,883 Da
Basal Isoelectric point: 9.17  Predict pI for various phosphorylation states
Select Structure to View Below

GSX1

Protein Structure Not Found.


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Modification Sites and Domains  

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 S235‑p GCKCASLssAKCSED
0 1 S236‑p CKCASLssAKCSEDD
0 2 S249‑p DDDELPMsPsssGKD
0 2 S251‑p DELPMsPsssGKDDR
0 2 S252‑p ELPMsPsssGKDDRD
0 2 S253‑p LPMsPsssGKDDRDL
  mouse

 
S232 GCKCSSLSSAKCSED
S233 CKCSSLSSAKCSEDD
S246 DDDELPMSPsssGKD
S248‑p DELPMSPsssGKDDR
S249‑p ELPMSPsssGKDDRD
S250‑p LPMSPsssGKDDRDL
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