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C22orf29
Could induce apoptosis in a BH3 domain-dependent manner. The direct interaction network of Bcl-2 family members may play a key role in modulation BOP intrinsic apoptotic signaling activity. Interacts (via BH3 domain) with VDAC1. Interacts with pro-survival Bcl-2 family members, BCL2, BCL2L1 isoform Bcl-X(L), MCL1, BCL2A1 and BCL2L2. Interacts with BAX and BAK.
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| Chromosomal Location of Human Ortholog: 22q11.21 |
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Cellular Component: mitochondrion
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Molecular Function: protein binding
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Biological Process: regulation of mitochondrial membrane potential
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Reference #:
Q7L3V2
(UniProtKB)
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Alt. Names/Synonyms: C22orf29; chromosome 22 open reading frame 29; CV029; FLJ21125; hypothetical protein LOC79680; Uncharacterized protein C22orf29
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Gene Symbols: C22orf29
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Molecular weight:
39,299 Da
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Basal Isoelectric point:
4.93
Predict pI for various phosphorylation states
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