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Protein Page:
LTBR (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitylation
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
LTBR Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 12p13
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: identical protein binding; protein binding; tumor necrosis factor receptor activity; ubiquitin protein ligase binding
Biological Process: apoptosis; immune response; inflammatory response; multicellular organismal development; myeloid dendritic cell differentiation; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JNK cascade; regulation of cell proliferation; response to lipopolysaccharide; signal transduction; tumor necrosis factor-mediated signaling pathway; viral reproduction
Reference #:  P36941 (UniProtKB)
Gene Symbols: LTBR
Molecular weight: 46,709 Da
Basal Isoelectric point: 5.53  Predict pI for various phosphorylation states
CST Pathways:  NF-kB Signaling
Select Structure to View Below

LTBR

Protein Structure Not Found.
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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 K257‑ub SHPSLCRkLGsLLKR
0 1 S260‑p SLCRkLGsLLKRRPQ
0 1 S323‑p AGVPQQQsPLDLTRE
0 2 T421‑p ETEHCGAtPsNRGPR
0 1 T421‑gl ETEHCGAtPsNRGPR
0 1 S423‑gl EHCGAtPsNRGPRNQ
  mouse

 
K253 RHPSLCRKLGTLLKR
T256 SLCRKLGTLLKRHPE
S315 EVVLQQQSPLVQARE
- gap
- gap
- gap
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