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Protein Page:
HEFL (human)

HEFL Docking protein that plays a role in tyrosine kinase- based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading. Belongs to the CAS family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 20q13.31
Reference #:  Q9NQ75 (UniProtKB)
Alt. Names/Synonyms: C20orf32; Cas scaffolding protein family member 4; CAS4; CASS4; HEF-like protein; HEF1-EFS-p130Cas-like protein; HEFL; HEPL
Gene Symbols: CASS4
Molecular weight: 87,144 Da
Basal Isoelectric point: 6.66  Predict pI for various phosphorylation states
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Protein Structure Not Found.
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