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Protein Page:
UTX (human)

UTX a nuclear protein that contains 8 tetratrico peptide repeat (TPRs). Processes involving TPR proteins include cell-cycle control, transcription repression, stress response, protein kinase inhibition, mitochondrial and peroxisomal protein transport and neurogenesis. Note: This description may include information from UniProtKB.
Protein type: EC 1.14.11.-; Oxidoreductase
Chromosomal Location of Human Ortholog: Xp11.3
Cellular Component: histone methyltransferase complex; nucleoplasm; nucleus
Molecular Function: histone demethylase activity
Biological Process: histone H3-K4 methylation
Disease: Kabuki Syndrome 1; Kabuki Syndrome 2
Reference #:  O15550 (UniProtKB)
Alt. Names/Synonyms: bA386N14.2; bA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX)); DKFZp686A03225; Histone demethylase UTX; KDM6A; lysine (K)-specific demethylase 6A; Lysine-specific demethylase 6A; MGC141941; Ubiquitously transcribed TPR protein on the X chromosome; Ubiquitously transcribed X chromosome tetratricopeptide repeat protein; ubiquitously-transcribed TPR gene on the X chromosome; UTX
Gene Symbols: KDM6A
Molecular weight: 154,177 Da
Basal Isoelectric point: 7.17  Predict pI for various phosphorylation states
CST Pathways:  Histone Methylation
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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