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Protein Page:
MMP10 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitylation
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
MMP10 Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase. Belongs to the peptidase M10A family. Note: This description may include information from UniProtKB.
Protein type: Protease; Secreted, signal peptide; Secreted; Extracellular matrix; EC 3.4.24.22
Chromosomal Location of Human Ortholog: 11q22.3
Cellular Component: extracellular region; extracellular space
Molecular Function: serine-type endopeptidase activity
Biological Process: collagen catabolic process; extracellular matrix disassembly
Reference #:  P09238 (UniProtKB)
Alt. Names/Synonyms: matrix metallopeptidase 10 (stromelysin 2); matrix metalloprotease 10; matrix metalloproteinase 10 (stromelysin 2); Matrix metalloproteinase-10; MMP-10; MMP10; SL-2; STMY2; stromelysin 2; Stromelysin-2; transin 2; Transin-2
Gene Symbols: MMP10
Molecular weight: 54,151 Da
Basal Isoelectric point: 5.49  Predict pI for various phosphorylation states
CST Pathways:  Angiogenesis  |  GPCR Signaling to MAPKs
Select Structure to View Below

MMP10

Protein Structure Not Found.
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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment



 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 N30 AAKEEDSNKDLAQQY
0 1 K54‑ac DVKQFRRkDSNLIVK
0 1 K62‑ac DSNLIVKkIQGMQKF
0 2 S281‑p VPTKSVPsGsEMPAK
0 1 S283‑p TKSVPsGsEMPAKCD
  mouse

 
S30‑p AVTQGHPsMDLAQQY
K55 EKQIFKRKDSSPVVK
K63 DSSPVVKKIQEMQKF
S280 VVPVLSVSPRPETPD
P283 VLSVSPRPETPDKCD
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