Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3. Belongs to the intercrine alpha (chemokine CxC) family. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide
Biological Process: cell-cell signaling; cellular defense response; chemotaxis; defense response; G-protein coupled receptor protein signaling pathway; immune response; inflammatory response; positive regulation of cAMP metabolic process; positive regulation of leukocyte chemotaxis; positive regulation of release of sequestered calcium ion into cytosol; regulation of cell proliferation; response to lipopolysaccharide; signal transduction