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Protein Page:
TAF1L (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitylation
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
TAF1L May act as a functional substitute for TAF1/TAFII250 during male meiosis, when sex chromosomes are transcriptionally silenced. Belongs to the TAF1 family. Note: This description may include information from UniProtKB.
Protein type: Transcription initiation complex; DNA-binding; Kinase, protein; Protein kinase, atypical; ATYPICAL group; TAF1 family
Chromosomal Location of Human Ortholog: 9p21.1
Cellular Component: nucleoplasm
Molecular Function: histone acetyltransferase activity; protein serine/threonine kinase activity; TATA-binding protein binding
Biological Process: male meiosis; positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; RNA elongation from RNA polymerase II promoter; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter
Reference #:  Q8IZX4 (UniProtKB)
Alt. Names/Synonyms: MGC134910; TAF(II)210; TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like; TAF1L; TAF2A2; TBP-associated factor 1-like; TBP-associated factor 210 kDa; TBP-associated factor RNA polymerase 1-like; Transcription initiation factor TFIID 210 kDa subunit; Transcription initiation factor TFIID subunit 1-like
Gene Symbols: TAF1L
Molecular weight: 207,302 Da
Basal Isoelectric point: 5.26  Predict pI for various phosphorylation states
Select Structure to View Below

TAF1L

Protein Structure Not Found.
Download PyMol Script
Download ChimeraX Script


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment



 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 S543‑p KEEATSNsPSKESKK
0 1 T564‑p SRILLGKtGVIREEP
0 2 K720‑ub VGMATKIkNYYkRKP
0 20 K724‑ac TKIkNYYkRKPGKDP
0 1 K724‑ub TKIkNYYkRKPGKDP
0 1 T1173‑p DDVTASMtsLKSSAT
0 1 S1174‑p DVTASMtsLKSSATG
0 2 K1263‑ac NQEKEKLkGPPEKKP
0 2 S1359‑p VHEVRRKsLVLKFPk
0 1 K1366‑ac sLVLKFPkQQLPPKk
0 1 K1373‑ac kQQLPPKkKRRVGTT
0 1 Y1385‑p GTTVHCDyLNIPHKS
0 1 T1398‑p KSIHRRRtDPMVtLS
0 1 T1403‑p RRtDPMVtLSSILES
0 1 Y1560‑p KKFVPDYyKMIVNPV
0 1 Y1669‑p TSQPPDMyDTNTSLS
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