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Protein Page:
IL17A (human)

Overview
IL17A Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. Belongs to the IL-17 family. Note: This description may include information from UniProtKB.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 6p12
Cellular Component: extracellular region
Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor binding; protein binding
Biological Process: apoptosis; cell death; cell surface receptor linked signal transduction; cell-cell signaling; immune response; inflammatory response; positive regulation of interleukin-23 production; positive regulation of osteoclast differentiation; positive regulation of transcription from RNA polymerase II promoter
Reference #:  Q16552 (UniProtKB)
Alt. Names/Synonyms: CTLA-8; CTLA8; Cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; cytotoxic T-lymphocyte-associated serine esterase 8; IL-17; IL-17A; IL17; IL17A; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17A; Interleukin-17A
Gene Symbols: IL17A
Molecular weight: 17,504 Da
Basal Isoelectric point: 8.82  Predict pI for various phosphorylation states
Select Structure to View Below

IL17A

Protein Structure Not Found.
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