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Protein Page:
CCNA2 (human)

CCNA2 a member of the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions. Note: This description may include information from UniProtKB.
Protein type: Cell cycle regulation; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 4q27
Cellular Component: cytoplasm; Golgi apparatus; nucleoplasm; nucleus
Molecular Function: protein binding
Biological Process: mitotic cell cycle G2/M transition DNA damage checkpoint; Ras protein signal transduction
Reference #:  P20248 (UniProtKB)
Alt. Names/Synonyms: CCN1; CCNA; CCNA2; cyclin A2; Cyclin-A; Cyclin-A2
Gene Symbols: CCNA2
Molecular weight: 48,551 Da
Basal Isoelectric point: 6.1  Predict pI for various phosphorylation states
CST Pathways:  AMPK Signaling
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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