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BOK
May play a role in apoptosis. Belongs to the Bcl-2 family. Note: This description may include information from UniProtKB.
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| Chromosomal Location of Human Ortholog: 2q37.3 |
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Cellular Component: cytoplasm; early endosome membrane; endoplasmic reticulum; endoplasmic reticulum membrane; Golgi apparatus; mitochondrial inner membrane; mitochondrial membrane; mitochondrial outer membrane; mitochondrion; nucleus; recycling endosome membrane; trans-Golgi network membrane
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Molecular Function: protein binding; protein heterodimerization activity; protein homodimerization activity
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Biological Process: apoptosis; caspase activation; caspase activation via cytochrome c; cell proliferation; cell structure disassembly during apoptosis; DNA damage response, signal transduction resulting in induction of apoptosis; positive regulation of apoptosis; protein oligomerization; regulation of autophagy; release of cytochrome c from mitochondria
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Reference #:
Q9UMX3
(UniProtKB)
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Alt. Names/Synonyms: Bcl-2-like protein 9; Bcl-2-related ovarian killer protein; Bcl2-L-9; BCL2-related ovarian killer; BCL2L9; BOK; BOKL; hBOK; MGC4631
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Gene Symbols: BOK
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Molecular weight:
23,280 Da
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Basal Isoelectric point:
9.33
Predict pI for various phosphorylation states
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Protein-Specific Antibodies or siRNAs from Cell Signaling Technology®
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