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Protein Page:
KILLIN (human)

Overview
KILLIN DNA-binding protein involved in S phase checkpoint control-coupled apoptosis by mediating p53/TP53-induced apoptosis. Has the ability to inhibit DNA synthesis and S phase arrest coupled to apoptosis. Has affinity to both double- and single- stranded DNA. Note: This description may include information from UniProtKB.
Chromosomal Location of Human Ortholog: 10q23
Cellular Component: nucleolus; nucleus
Molecular Function: DNA binding
Biological Process: apoptosis; cell cycle arrest
Disease: Cowden Syndrome 4
Reference #:  B2CW77 (UniProtKB)
Alt. Names/Synonyms: B2CW77; killin protein
Gene Symbols: KLLN
Molecular weight: 19,958 Da
Basal Isoelectric point: 11.27  Predict pI for various phosphorylation states
Select Structure to View Below

KILLIN

Protein Structure Not Found.


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Modification Sites and Domains  

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 S35‑p NGRKLQPsEWAGRGD
0 1 S90‑p SGGKSSSsFARGALA
0 1 T113‑p PSCAAAEtGARTSLP
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