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Protein Page:
ADH1C (human)

Overview
ADH1C class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. [provided by RefSeq, Jul 2008]
Protein type: Amino Acid Metabolism - tyrosine; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Cofactor and Vitamin Metabolism - retinol; EC 1.1.1.1; Lipid Metabolism - fatty acid; Mitochondrial; Oxidoreductase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450
Chromosomal Location of Human Ortholog: 4q23
Cellular Component: cytosol
Molecular Function: alcohol dehydrogenase activity; alcohol dehydrogenase activity, zinc-dependent; retinol dehydrogenase activity
Biological Process: ethanol oxidation
Disease: Alcohol Dependence; Parkinson Disease, Late-onset
Reference #:  P00326 (UniProtKB)
Alt. Names/Synonyms: ADH, gamma subunit; ADH1C; ADH1G; ADH3; Alcohol dehydrogenase 1C; alcohol dehydrogenase 1C (class I), gamma polypeptide; alcohol dehydrogenase 3 (class I), gamma polypeptide; Alcohol dehydrogenase subunit gamma
Gene Symbols: ADH1C
Molecular weight: 39,868 Da
Basal Isoelectric point: 8.63  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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ADH1C

Protein Structure Not Found.
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