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Protein Page:
NAT6 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitylation
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
NAT6 Seems to be involved in N-acetylation. Acts on peptides with a N-terminal Met followed by Asp/Glu/Asn. May act as a tumor suppressor. Belongs to the acetyltransferase family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: EC 2.3.1.-; Tumor suppressor; Secondary Metabolites Metabolism - limonene and pinene degradation; Amino Acid Metabolism - phenylalanine; Acetyltransferase; Amino Acid Metabolism - tyrosine; Lipid Metabolism - glycerophospholipid
Chromosomal Location of Human Ortholog: 3p21.3
Reference #:  Q93015 (UniProtKB)
Alt. Names/Synonyms: FUS-2; FUS2; N-acetyltransferase 6; N-acetyltransferase 6 (GCN5-related); NAT6; Protein fus-2; Protein fusion-2; putative tumor suppressor
Gene Symbols: NAT6
Molecular weight: 31,445 Da
Basal Isoelectric point: 7.75  Predict pI for various phosphorylation states
Select Structure to View Below

NAT6

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment



 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

► Hide Isoforms
 
0 2 - gap
0 2 - gap
0 1 S6 __MELILStsPAELT
0 2 T7‑p _MELILStsPAELTL
0 3 S8‑p MELILStsPAELTLD
0 2 - gap
0 4 P205 VFTSRRLPATLLNAF
0 1 T207 TSRRLPATLLNAFPT
0 10 S217‑p NAFPTAPsPRPPRKA
0 3 S254‑p LPECLTIsPPVPSGP
0 2 P258 LTIsPPVPSGPPSKS
0 1 S265 PSGPPSKSLLETQyQ
0 6 Y271‑p KSLLETQyQNVRGRP
0 2 R275 ETQyQNVRGRPIFWM
  NAT6 iso2  
S7‑p _MQELTLsPGPAKLt
T14‑p sPGPAKLtPTLDPTH
S28 HRMELILSTsPAELT
T29 RMELILSTsPAELTL
S30‑p MELILSTsPAELTLD
- gap
P227 VFTSRRLPATLLNAF
T229 TSRRLPATLLNAFPT
S239 NAFPTAPSPRPPRKA
S276 LPECLTISPPVPSGP
P280 LTISPPVPSGPPSKS
S287 PSGPPSKSLLETQYQ
Y293 KSLLETQYQNVRGRP
R297 ETQYQNVRGRPIFWM
  mouse

 
- gap
- gap
S6‑p __MELILstsPAKLT
T7‑p _MELILstsPAKLTL
S8‑p MELILstsPAKLTLD
S44‑p RQPELSLsPRLAELT
S233‑p AFTNRRLsTtVLRAF
T235‑p TNRRLsTtVLRAFSK
C245 RAFSKPPCPQPPCKE
S282 LPQSLTASPPPsPEP
S286‑p LTASPPPsPEPLPQs
S293‑p sPEPLPQsPLETCYR
Y299 QsPLETCYRDLkGCP
K303‑ac ETCYRDLkGCPIFWM
  rat

 
- gap
- gap
S6 __MELILSTSPAKLT
T7 _MELILSTSPAKLTL
S8 MELILSTSPAKLTLD
S44‑p RQSELSLsPRLAELT
P233 AFTNRRLPTNVLRAF
N235 TNRRLPTNVLRAFSK
C245 RAFSKPPCPQPPCKA
S280 PPLPLTTSPPPsPEP
S284‑p LTTSPPPsPEPLPQS
S291 sPEPLPQSPLETRYR
Y297 QSPLETRYRDLkGCP
K301‑ac ETRYRDLkGCPIFWM
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