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Protein Page:
LAMP1 (human)
rdtyret
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitylation
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
LAMP1 Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis. Belongs to the LAMP family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 13q34
Cellular Component: cell soma; cytoplasm; dendrite; endosome membrane; external side of plasma membrane; integral to plasma membrane; late endosome; lysosomal membrane; lysosome; melanosome; membrane; multivesicular body; perinuclear region of cytoplasm; plasma membrane; sarcolemma; synaptic vesicle
Molecular Function: enzyme binding; protein binding; protein domain specific binding; viral receptor activity
Biological Process: autophagic cell death; autophagy; entry of virus into host cell; induction of apoptosis by granzyme; positive regulation of natural killer cell degranulation; positive regulation of natural killer cell mediated cytotoxicity; protein stabilization
Reference #:  P11279 (UniProtKB)
Alt. Names/Synonyms: CD107 antigen-like family member A; CD107a; LAMP-1; LAMP1; LAMPA; LGP120; lysosomal-associated membrane protein 1; Lysosome-associated membrane glycoprotein 1; Lysosome-associated membrane protein 1
Gene Symbols: LAMP1
Molecular weight: 44,882 Da
Basal Isoelectric point: Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

LAMP1

Protein Structure Not Found.


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Modification Sites and Domains  
Click here to view other types of protein modifications

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 S27‑p LGLMHCAsAAMFMVK
0 1 S69‑p NMTFDLPsDAtVVLN
0 1 T72‑p FDLPsDAtVVLNRss
0 1 S78‑p AtVVLNRssCGKENt
0 1 S79‑p tVVLNRssCGKENtS
0 1 T85‑p ssCGKENtSDPSLVI
0 1 K137‑sc NASSKEIkTVESITD
0 1 S157 DKKYRCVSGTQVHMN
0 1 S197‑ga RCEQDRPsPttAPPA
0 1 T199‑ga EQDRPsPttAPPAPP
0 1 T200‑ga QDRPsPttAPPAPPs
0 1 S207‑ga tAPPAPPsPsPsPVP
0 1 S209‑ga PPAPPsPsPsPVPKS
0 1 S211‑ga APPsPsPsPVPKSPS
0 1 T230‑p NVSGTNGtCLLASMG
0 1 K247 LNLTYERKDNTTVTR
0 1 K319‑ub DARDPAFkAANGSLR
0 1 T331‑ga SLRALQAtVGNSyKC
0 3 Y336‑p QAtVGNSyKCNAEEH
0 1 S351‑p VRVTKAFsVNIFKVW
0 13 Y414‑p RKRSHAGyQTI____
  mouse

 
S23 AGLAHGASALFEVKN
- gap
- gap
S72 AEVLKNGSSCGKENV
S73 EVLKNGSSCGKENVS
V79 SSCGKENVSDPSLTI
Y131 NAISKEIYTMDSTTD
S151‑p NKAYRCVsDIRVYMK
S191 HCTQDGPSPTTGPPS
T193 TQDGPSPTTGPPSPS
T194 QDGPSPTTGPPSPSP
S198 SPTTGPPSPSPPLVP
S200 TTGPPSPSPPLVPTN
P202 GPPSPSPPLVPTNPT
T221 NVTGNNGTCLLASMA
K238‑ac LNITYLKkDNKTVTR
S308 DALVPTFSISNHSLK
T320 SLKALQATVGNSYKC
Y325 QATVGNSYKCNTEEH
S340 IFVSKMLSLNVFSVQ
Y403 RKRSHAGYQTI____
  rat

 
P23 AGLAHSAPALFEVKD
- gap
- gap
S73 AEVLKNSSSCGEKNA
S74 EVLKNSSSCGEKNAS
A80 SSCGEKNASEPTLAI
D132 NASSKGPDTVDSTTD
S152 NKTYRCVSDIRVYMK
S192 RCPQDQPSPTTGPPS
T194 PQDQPSPTTGPPSPS
T195 QDQPSPTTGPPSPSP
S199 SPTTGPPSPSPPLVP
S201 TTGPPSPSPPLVPTN
P203 GPPSPSPPLVPTNPS
T222 NVTGDNGTCLLASMA
K239 LNITYMKKDNTTVTR
S309 DAIEPTFSTSNYSLK
S321 SLKALQASVGNSYKC
Y326 QASVGNSYKCNSEEH
A341 IFVSKALALNVFSVQ
Y404 RKRSHAGYQTI____
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