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Protein Page:
NUPL2 (human)

Overview
NUPL2 Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Nucleoporin
Chromosomal Location of Human Ortholog: 7p15
Cellular Component: cytoplasm; cytosol; nuclear envelope; nucleoplasm; nucleus
Molecular Function: nuclear export signal receptor activity; protein binding
Biological Process: mitotic nuclear envelope disassembly; mRNA export from nucleus; protein export from nucleus; protein sumoylation; RNA-mediated gene silencing; tRNA export from nucleus; viral reproduction; viral transcription
Reference #:  O15504 (UniProtKB)
Alt. Names/Synonyms: CG1; H_RG271G13.9; hCG1; NLP-1; NLP_1; Nucleoporin hCG1; nucleoporin like 2; nucleoporin-like protein 1; Nucleoporin-like protein 2; NUP42 homolog; NUPL2
Gene Symbols: NUPL2
Molecular weight: 44,872 Da
Basal Isoelectric point: 9.25  Predict pI for various phosphorylation states
Select Structure to View Below

NUPL2

Protein Structure Not Found.


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